Selection of Internal and External Publications
Listed below are 356 publications (sorted according to the PDB release date) from 698 structures citing the X-ray diffraction experiments at BESSY-MX beamlines.
Last updated 19.04.2012
2012
- Thermal unfolding studies of cold adapted uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua). A comparative study with human UNG.
Assefa, N.G., Niiranen, L., Willassen, N.P., Smalas, A., Moe, E.
Comp.Biochem.Physiol. B: Biochem.Mol.Biol. 161, pp. 60 - RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution.
Sachs, R., Max, K.E., Heinemann, U., Balbach, J.
Rna 18, pp. 65 - Structural and Biochemical Basis of Lectin Yos9 Dimerization and Possible Contribution to Self-Association of the Hmg-Coa Reductase Degradation (Hrd) Ubiquitin-Ligase Complex
Hanna, J., Schuetz, A., Zimmermann, F., Behlke, J., Sommer, T., Heinemann, U.
J.Biol.Chem. , pp. - Structure of the effector-binding domain of the arabinose repressor AraR from Bacillus subtilis
Prochazkova, K., Cermakova, K., Pachl, P., Sieglova, I., Otwinowski, Z., Fabry, M., Rezacova, P.
Acta Crystallogr.,Sect.D D68, pp. 176 - Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain.
Dahms, S.O., Konnig, I., Roeser, D., Guhrs, K.H., Mayer, M.C., Kaden, D., Multhaup, G., Than, M.E.
J.Mol.Biol. , pp. - The Fe(II) / alpha-ketoglutarate dependent taurine dioxygenases from Pseudomonas putida and Escherichia coli are tetramers
Knauer, S.H., Hartl-Spiegelhauer, O., Schwarzinger, S., Hanzelmann, P., Dobbek, H.
Febs J. , pp. - Structure of the Yersinia Pestis Fabv Enoyl-Acp Reductase and its Interaction with Two 2-Pyridone Inhibitors
Hirschbeck, M.W., Kuper, J., Lu, H., Liu, N., Neckles, C., Shah, S., Wagner, S., Sotriffer, C.A., Tonge, P.J., Kisker, C.
Structure 20, pp. 89 - Interaction of Mxig with the Cytosolic Complex of the Type III Secretion System Controls Shigella Virulence.
Barison, N., Lambers, J., Hurwitz, R., Kolbe, M.
Faseb J. , pp. - Structural Insights Into the Redox-Switch Mechanism of the Marr/Duf24-Type Regulator Hypr
Palm, G.J., Chi, B.K., Waack, P., Gronau, K., Becher, D., Albrecht, D., Hinrichs, W., Read, R.J., Antelmann, H.
Nucleic Acids Res. , pp. - Tail morphology controls DNA release in two Salmonella phages with one lipopolysaccharide receptor recognition system.
Andres, D., Roske, Y., Doering, C., Heinemann, U., Seckler, R., Barbirz, S.
Mol.Microbiol. 83, pp. 1244 - The crystal structure of protease Sapp1p from Candida parapsilosis in complex with the HIV protease inhibitor ritonavir.
Dostal, J., Brynda, J., Hruskova-Heidingsfeldova, O., Pachl, P., Pichova, I., Rezacova, P.
J Enzyme Inhib Med Chem 27, pp. 160 - Synthesis, Structure-Activity Relationship Studies and X ray Crystallographic Analysis of Arylsulfonamides as Potent Carbonic Anhydrase Inhibitors.
Gitto, R., Damiano, F.M., Mader, P., De Luca, L., Ferro, S., Supuran, C.T., Vullo, D., Brynda, J., Rezacova, P., Chimirri, A.
J.Med.Chem. - Redox-Dependent Complex Formation by an ATP-Dependent Activator of the Corrinoid/Iron-Sulfur Protein.
Hennig, S.E., Jeoung, J.H., Goetzl, S., Dobbek, H.
Proc.Natl.Acad.Sci.USA 109, pp. 5235 - N-Butyl Isocyanide Oxidation at the [Nife4S4Oh(X)] Cluster of Co Dehydrogenase.
Jeoung, J.H., Dobbek, H.
J.Biol.Inorg.Chem. 17, pp. 167 - Crystal Structures of N-Acetylmannosamine Kinase Provide Insights Into Enzyme Specificity and Inhibition
Martinez, J., Nguyen, L.D., Tauberger, E., Hinderlich, S., Reutter, W., Fan, H., Saenger, W., Moniot, S.
J.Biol.Chem. - Crystal structure and functional characterization of a glucosamine-6-phosphate N-acetyltransferase from Arabidopsis thaliana.
Riegler, H., Herter, T., Grishkovskaya, I., Lude, A., Ryngajllo, M., Bolger, M.E., Essigmann, B., Usadel, B.
Biochem.J. 443, pp. 427 - Moonlighting by Different Stressors: Crystal Structure of the Chaperone Species of a 2-Cys Peroxiredoxin.
Saccoccia, F., Di Micco, P., Boumis, G., Brunori, M., Koutris, I., Miele, A.E., Morea, V., Sriratana, P., Williams, D.L., Bellelli, A., Angelucci, F.
Structure 20, pp. 429 - The extra-domain B in oncofetal fibronectin promotes fibrillar head-to-tail dimerization of this extracellular matrix protein via a structural mechanism
Schiefner, A., Gebauer, M., Skerra, A.
J.Biol.Chem. - Crystal structure of a supercharged variant of the human enteropeptidase light chain
Simeonov, P., Zahn, M., Straeter, N., Zuchner, T.
Proteins - Non-structural Proteins 7 and 8 of Feline Coronavirus Form a 2:1 Heterotrimer that Exhibits Primer-independent RNA Polymerase Activity.
Xiao, Y., Ma, Q., Restle, T., Shang, W., Svergun, D.I., Ponnusamy, R., Sczakiel, G., Hilgenfeld, R.
J.Virol. - Facilities for Macromolecular Crystallography at the Helmholtz-Zentrum Berlin.
Mueller, U., Darowski, N., Fuchs, M.R., Förster, R., Hellmig, M., Paithankar, K.S., Pühringer, S., Steffien, M., G., Z., Weiss, M.S
J. Synch. Rad. 19, pp. 442 - XDSAPP: a graphical user interface for the convenient processing of diffraction data using XDS.
Krug, M., Weiss, M. S., Heinemann, U., Mueller, U.
J. Appl. Cryst. , pp.
2011
- Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania Infantum Proliferation
Baiocco, P., Colotti, G., Ilari, A.
Acs Med.Chem.Lett 2, pp. 230 - Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni2+ and Zn2+ reveal a role for the disordered C-terminal arm in metal trafficking.
Banaszak, K., Martin-Diaconescu, V., Bellucci, M., Zambelli, B., Rypniewski, W., Maroney, M.J., Ciurli, S.
Biochem.J. , pp. - Structural basis of the reduced affinity between the protein kinase CK2 subunits CK2alpha prime and CK2beta
Bischoff, N., Olsen, B., Raaf, J., Bretner, M., Issinger, O.G., Niefind, K.
J.Mol.Biol. , pp. - Two Solutions for the Same Problem: Multiple Binding Modes of Pyrrolidine-Based HIV-1 Protease Inhibitors
Blum, A., Bottcher, J., Dorr, S., Heine, A., Klebe, G., Diederich, W.E.
J.Mol.Biol. 410, pp. 745 - A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching.
Brakemann, T., Stiel, A.C., Weber, G., Andresen, M., Testa, I., Grotjohann, T., Leutenegger, M., Plessmann, U., Urlaub, H., Eggeling, C., Wahl, M.C., Hell, S.W., Jakobs, S.
Nat.Biotechnol. 29, pp. 942 - Crystal structures of the apo form of beta-fructofuranosidase from Bifidobacterium longum and its complex with fructose
Bujacz, A., Jedrzejczak-Krzepkowska, M., Bielecki, S., Redzynia, I., Bujacz, G.
Febs J. 278, pp. 1728 - Crystal Structures of Two Solute Receptors for L- Cystine and L-Cysteine, Respectively, of the Human Pathogen Neisseria Gonorrhoea.
Bulut, H., Moniot, S., Licht, A., Scheffel, F., Gathmann, S., Saenger, W., Schneider, E.
J.Mol.Biol. , pp. - Mechanism and Specificity of Pentachloropseudilin-Mediated Inhibition of Myosin Motor Activity.
Chinthalapudi, K., Taft, M.H., Martin, R., Heissler, S.M., Preller, M., Hartmann, F.K., Brandstaetter, H., Kendrick-Jones, J., Tsiavaliaris, G., Gutzeit, H.O., Fedorov, R., Buss, F., Knoelker, H.J., Coluccio, L.M., Manstein, D.J.
J.Biol.Chem. 286, pp. 29700 - Crystal structure of metarhodopsin II.
Choe, H.W., Kim, Y.J., Park, J.H., Morizumi, T., Pai, E.F., Krauss, N., Hofmann, K.P., Scheerer, P., Ernst, O.P.
Nature 471, pp. 651 - Endothelium-Protective Sphingosine-1-Phosphate Provided by Hdl-Associated Apolipoprotein M.
Christoffersen, C., Obinata, H., Kumaraswamy, S.B., Galvani, S., Ahnstrom, J., Sevvana, M., Egerer-Sieber, C., Muller, Y.A., Hla, T., Nielsen, L.B., Dahlback, B.
Proc.Natl.Acad.Sci.USA 108, pp. 9613 - Structural Basis for Complex Formation between Human Irsp53 and the Translocated Intimin Receptor Tir of Enterohemorrhagic E. Coli.
De Groot, J.C., Schluter, K., Carius, Y., Quedenau, C., Faix, D.Vingadassalo J., Weiss, S.M., Reichelt, J., Standfuss-Gabisch, C., Lesser, C.F., Leong, J.M., Heinz, D.W., Bussow, K., Stradal, T.E.B.
Structure 19, pp. 1294 - Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major.
Dickmanns, A., Damerow, S., Neumann, P., Schulz, E.C., Lamerz, A.C., Routier, F.H., Ficner, R.
J.Mol.Biol. 405, pp. 461 - Structure of Collagenase G Reveals a Chew-and -Digest Mechanism of Bacterial Collagenolysis
Eckhard, U., Schoenauer, E., Nuess, D., Brandstetter, H.
Nat.Struct.Mol.Biol. 18, pp. 1109 - Crystal structure of the sensory domain of Escherichia coli CadC, a member of the ToxR-like protein family.
Eichinger, A., Haneburger, I., Koller, C., Jung, K., Skerra, A.
Protein Sci. 20, pp. 656 - Crystal structure of nucleotide-free dynamin.
Faelber, K., Posor, Y., Gao, S., Held, M., Roske, Y., Schulze, D., Haucke, V., Noe, F., Daumke, O.
Nature 477, pp. 556 - Crystal Structure Analysis Reveals Functional Flexibility in the Selenocysteine-Specific tRNA from Mouse
Ganichkin, O.M., Anedchenko, E.A., Wahl, M.C.
PLoS ONE 6, pp. 20032 - Structure of myxovirus resistance protein a reveals intra- and intermolecular domain interactions required for the antiviral function.
Gao, S., von der Malsburg, A., Dick, A., Faelber, K., Schroder, G.F., Haller, O., Kochs, G., Daumke, O.
Immunity 35, pp. 514 - Structural Basis for Electron and Methyl-Group Transfer in a Methyltransferase System Operating in the Reductive Acetyl-Coa Pathway
Goetzl, S., Jeoung, J.H., Hennig, S.E., Dobbek, H.
J.Mol.Biol. 411, pp. 96 - Crystal structure of a copper-transporting PIB-type ATPase.
Gourdon, P., Liu, X.Y., Skjorringe, T., Morth, J.P., Moller, L.B., Pedersen, B.P., Nissen, P.
Nature 475, pp. 59 - Structural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium.
Hansen, G., Heitmann, A., Witt, T., Li, H., Jiang, H., Shen, X., Heussler, V.T., Rennenberg, A., Hilgenfeld, R.
Structure 19, pp. 919 - Hierarchical Binding of Cofactors to the AAA ATPase p97.
Hanzelmann, P., Buchberger, A., Schindelin, H.
Structure 19, pp. 833 - The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97.
Hanzelmann, P., Schindelin, H.
J.Biol.Chem. 286, pp. 38679 - The X-Ray Structure of the Zinc Transporter Znua from Salmonella Enterica Discloses a Unique Triad of Zinc Coordinating Histidines.
Ilari, A., Alaleona, F., Petrarca, P., Battistoni, A., Chiancone, E.
J.Mol.Biol. 409, pp. 630 - Structure of UvrA nucleotide excision repair protein in complex with modified DNA.
Jaciuk, M., Nowak, E., Skowronek, K., Tanska, A., Nowotny, M.
Nat.Struct.Mol.Biol. 18, pp. 191 - Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome.
Kiliszek, A., Kierzek, R., Krzyzosiak, W.J., Rypniewski, W.
Nucleic Acids Res. 39, pp. 7308 - Rational Design of Oncocin Derivatives with Superior Protease Stabilities and Antibacterial Activities Based on the High-Resolution Structure of the Oncocin-DnaK Complex.
Knappe, D., Zahn, M., Sauer, U., Schiffer, G., Strater, N., Hoffmann, R.
Chembiochem 12, pp. 874 - Structural Basis for Reductive Radical Formation and Electron Recycling in (R)-2-Hydroxyisocaproyl-CoA Dehydratase.
Knauer, S.H., Buckel, W., Dobbek, H.
J.Am.Chem.Soc. 133, pp. 4342 - Tracing the detail: how mutations affect binding modes and thermodynamic signatures of closely related aldose reductase inhibitors
Koch, C., Heine, A., Klebe, G.
J.Mol.Biol. 406, pp. 700 - Ligand-induced fit affects binding modes and provokes changes in crystal packing of aldose reductase
Koch, C., Heine, A., Klebe, G.
Biochim.Biophys.Acta 1810, pp. 879 - Radiation damage reveals promising interaction position
Koch, C., Heine, A., Klebe, G.
J.SYNCHROTRON RADIAT. 18, pp. 782 - Structure of the H107R variant of the extracellular domain of mouse NKR-P1A at 2.3 A resolution
Kolenko, P., Rozbesky, D., Vanek, O., Bezouska, K., Hasek, J., Dohnalek, J.
Acta Crystallogr.,Sect.F 67, pp. 1519 - A small nonrule of 3 compatible fragment library provides high hit rate of endothiapepsin crystal structures with various fragment chemotypes.
Koster, H., Craan, T., Brass, S., Herhaus, C., Zentgraf, M., Neumann, L., Heine, A., Klebe, G.
J.Med.Chem. 54, pp. 7784 - The Crystal Structure of Death Receptor 6 (DR6): A Potential Receptor of the Amyloid Precursor Protein (APP).
Kuester, M., Kemmerzehl, S., Dahms, S.O., Roeser, D., Than, M.E.
J.Mol.Biol. , pp. - Twisted Schiff base intermediates and substrate locale revise transaldolase mechanism.
Lehwess-Litzmann, A., Neumann, P., Parthier, C., Ludtke, S., Golbik, R., Ficner, R., Tittmann, K.
Nat.Chem.Biol. 7, pp. 678 - The Filamentous Phages Fd and If1 Use Different Mechanisms to Infect Escherichia Coli.
Lorenz, S.H., Jakob, R.P., Weininger, U., Balbach, J., Dobbek, H., Schmid, F.X.
J.Mol.Biol. 405, pp. 989 - Crystal Structure of Prgi-Sipd: Insight Into a Secretion Competent State of the Type Three Secretion System Needle Tip and its Interaction with Host Ligands
Lunelli, M., Hurwitz, R., Lambers, J., Kolbe, M.
Plos Pathog. 7, pp. 02163 - Crystal Structure of Prgi-Sipd: Insight Into a Secretion Competent State of the Type Three Secretion System Needle Tip and its Interaction with Host Ligands
Lunelli, M., Hurwitz, R., Lambers, J., Kolbe, M.
Plos Pathog. 7, pp. 02163 - A charge-sensitive loop in the FKBP38 catalytic domain modulates Bcl-2 binding.
Maestre-Martinez, M., Haupt, K., Edlich, F., Neumann, P., Parthier, C., Stubbs, M.T., Fischer, G., Luecke, C.
J.Mol.Recognit. 24, pp. 23 - Conformational Flexibility of the Ligand-Binding Domain Dimer in Kainate Receptor Gating and Desensitization
Nayeem, N., Mayans, O., Green, T.
J.Neurosci. 31, pp. 2916 - The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis.
Nilsson, E.C., Storm, R.J., Bauer, J., Johansson, S.M., Lookene, A., Angstrom, J., Hedenstrom, M., Eriksson, T.L., Frangsmyr, L., Rinaldi, S., Willison, H.J., Domellof, F.P., Stehle, T., Arnberg, N.
Nat Med 17, pp. 105 - Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Patton, G.C., Stenmark, P., Gollapalli, D.R., Sevastik, R., Kursula, P., Flodin, S., Schuler, H., Swales, C.T., Eklund, H., Himo, F., Nordlund, P., Hedstrom, L.
Nat.Chem.Biol. 7, pp. 950 - Mutants of protein kinase A that mimic the ATP-binding site of Aurora kinase
Pflug, A., de Oliveira, T.M., Bossemeyer, D., Engh, R.A.
Biochem.J. 440, pp. 85 - Structures of Glycosylated Mammalian Glutaminyl Cyclases Reveal Conformational Variability near the Active Center.
Ruiz-Carrillo, D., Koch, B., Parthier, C., Wermann, M., Dambe, T., Buchholz, M., Ludwig, H.H., Heiser, U., Rahfeld, J.U., Stubbs, M.T., Schilling, S., Demuth, H.U.
Biochemistry 50, pp. 6280 - Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the shank3 PDZ domain.
Saupe, J., Roske, Y., Schillinger, C., Kamdem, N., Radetzki, S., Diehl, A., Oschkinat, H., Krause, G., Heinemann, U., Rademann, J.
Chemmedchem 6, pp. 1411 - The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation.
Schuetz, A., Nana, D., Rose, C., Zocher, G., Milanovic, M., Koenigsmann, J., Blasig, R., Heinemann, U., Carstanjen, D.
Cell.Mol.Life Sci. 68, pp. 3121 - The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation.
Schuetz, A., Nana, D., Rose, C., Zocher, G., Milanovic, M., Koenigsmann, J., Blasig, R., Heinemann, U., Carstanjen, D.
Cell.Mol.Life Sci. 68, pp. 3121 - Structure analysis of Entamoeba histolytica enolase.
Schulz, E.C., Tietzel, M., Tovy, A., Ankri, S., Ficner, R.
Acta Crystallogr.,Sect.D 67, pp. 619 - Stereo- and Regioselective Azide/Alkyne Cycloadditions in Carbonic Anhydrase II via Tethering, Monitored by Crystallography and Mass Spectrometry.
Schulze Wischeler, J., Sun, D., Sandner, N.U., Linne, U., Heine, A., Koert, U., Klebe, G.
Chemistry 17, pp. 5842 - Stereo- and Regioselective Azide/Alkyne Cycloadditions in Carbonic Anhydrase II via Tethering, Monitored by Crystallography and Mass Spectrometry.
Schulze Wischeler, J., Sun, D., Sandner, N.U., Linne, U., Heine, A., Koert, U., Klebe, G.
Chemistry 17, pp. 5842 - Crystallographic Fragment Screen Identifies Cinnamic Acid Derivatives as Starting Points for Potent Pim-1 Inhibitors
Schulz, M.N., Fanghanel, J., Schafer, M., Badock, V., Briem, H., Boemer, U., Nguyen, D., Husemann, M., Hillig, R.C.
Acta Crystallogr.,Sect.D 67, pp. 156 - An Exclusive Alpha/Beta Code Directs Allostery in Tetr-Peptide Complexes.
Sevvana, M., Goetz, C., Goeke, D., Wimmer, C., Berens, C., Hillen, W., Muller, Y.A.
J.Mol.Biol. , pp. - Structure of laccase from Streptomyces coelicolor after soaking with potassium hexacyanoferrate and at an improved resolution of 2.3 A
Skalova, T., Duskova, J., Hasek, J., Stepankova, A., Koval, T., Ostergaard, L.H., Dohnalek, J.
Acta Crystallogr.,Sect.F 67, pp. 27 - A potent trivalent sialic Acid inhibitor of adenovirus type 37 infection of human corneal cells.
Spjut, S., Qian, W., Bauer, J., Storm, R., Frangsmyr, L., Stehle, T., Arnberg, N., Elofsson, M.
Angew.Chem.Int.Ed.Engl. 50, pp. 6519 - Crystal Structure of the Heme D1 Biosynthesis Enzyme Nire in Complex with its Substrate Reveals New Insights Into the Catalytic Mechanism of S-Adenosyl-L-Methionine-Dependent Uroporphyrinogen III Methyltransferases.
Storbeck, S., Saha, S., Krausze, J., Klink, B.U., Heinz, D.W., Layer, G.
J.Biol.Chem. 286, pp. 26754 - Molecular architecture and structural basis of allosteric regulation of eukaryotic phosphofructokinases.
Strater, N., Marek, S., Kuettner, E.B., Kloos, M., Keim, A., Bruser, A., Kirchberger, J., Schoneberg, T.
Faseb J. 25, pp. 89 - Polysaccharide Synthesis of the Levansucrase SacB from Bacillus megaterium Is Controlled by Distinct Surface Motifs.
Strube, C.P., Homann, A., Gamer, M., Jahn, D., Seibel, J., Heinz, D.W.
J.Biol.Chem. 286, pp. 17593 - Crystal Structure of Human Mth1 and the 8-Oxo-Dgmp Product Complex.
Svensson, L.M., Jemth, A., Desroses, M., Loseva, O., Helleday, T., Hogbom, M., Stenmark, P.
FEBS Lett. 585, pp. 2617 - Structure of the RuBisCO chaperone RbcX from the thermophilic cyanobacterium Thermosynechococcus elongatus
Tarnawski, M., Krzywda, S., Bialek, W., Jaskolski, M., Szczepaniak, A.
Acta Crystallogr.,Sect.F 67, pp. 851 - Comparative structural analysis of lipid binding START domains.
Thorsell, A.G., Lee, W.H., Persson, C., Siponen, M.I., Nilsson, M., Busam, R.D., Kotenyova, T., Schuler, H., Lehtio, L.
Plos One 6, pp. e19521 - Design of site-directed mutation transforming the overall shape of bacterial ribosomal protein L1
Tishchenko, S.V., Nikonova, E.Y., Kostareva, O., Gabdulkhakov, A.G., Piendl, W., Nikonov, S.V., Garber, M.B., Nevskaya, N.A.
Acta Crystallogr.,Sect.D 67, pp. 1023 - Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate.
Venskutonyte, R., Frydenvang, K., Gajhede, M., Bunch, L., Pickering, D.S., Kastrup, J.S.
J.Struct.Biol. , pp. - Structural Basis for a New Tetracycline Resistance Mechanism Relying on the Tetx Monooxygenase.
Volkers, G., Palm, G.J., Weiss, M.S., Wright, G.D., Hinrichs, W.
FEBS Lett. 585, pp. 1061 - Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition.
Von Kleist, L., Stahlschmidt, W., Bulut, H., Gromova, K., Puchkov, D., Robertson, M.J., Macgregor, K.A., Tomlin, N., Pechstein, A., Chau, N., Chircop, M., Sakoff, J., Von Kries, J.P., Saenger, W., Krausslich, H., Shupliakov, O., Robinson, P.J., Mccluskey, A., Haucke, V.
Cell 146, pp. 471 - Mechanism for Aar2p function as a U5 snRNP assembly factor.
Weber, G., Cristao, V.F., de L Alves, F., Santos, K.F., Holton, N., Rappsilber, J., Beggs, J.D., Wahl, M.C.
Genes Dev. 25, pp. 1601 - The Legionella HtrA homologue DegQ is a self-compartmentizing protease that forms large 12-meric assemblies.
Wrase, R., Scott, H., Hilgenfeld, R., Hansen, G.
Proc.Natl.Acad.Sci.USA 108, pp. 10490 - Crystal Structure and Domain Motion of Nucleoside Triphosphate Diphosphohydrolase (Ntpdase) 1
Zebisch, M., Schaefer, P., Krauss, M., Straeter, N.
J.Mol.Biol. , pp. - Crystallographic Evidence for a Domain Motion in Rat Nucleoside Triphosphate Diphosphohydrolase (Ntpdase) 1
Zebisch, M., Schaefer, P., Krauss, M., Straeter, N.
J.Mol.Biol. , pp. - Structural Basis for Two-component System Inhibition and Pilus Sensing by the Auxiliary CpxP Protein.
Zhou, X., Keller, R., Volkmer, R., Krauss, N., Scheerer, P., Hunke, S.
J.Biol.Chem. 286, pp. 9805 - Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease.
Zhu, L., George, S., Schmidt, M.F., Al-Gharabli, S.I., Rademann, J., Hilgenfeld, R.
Antiviral Res. 92, pp. 204 - Structural fine-tuning of a multifunctional cytochrome p450 monooxygenase.
Zocher, G., Richter, M.E., Mueller, U., Hertweck, C.
J.Am.Chem.Soc. 133, pp. 2292 - Mechanism for Aar2p function as a U5 snRNP assembly factor.
Weber, G., Cristao, V.F., de L Alves, F., Santos, K.F., Holton, N., Rappsilber, J., Beggs, J.D., Wahl, M.C.
Genes Dev. 25, pp. 1601
2010
- Mapping the Catalytic Cycle of Schistosoma Mansoni Thioredoxin Glutathione Reductase by X-Ray Crystallography
Angelucci, F., Dimastrogiovanni, D., Boumis, G., Brunori, M., Miele, A.E., Saccoccia, F., Bellelli, A.
J.Biol.Chem. 285, pp. 32557 - The Multi-Functional Protein in Peroxisomal Beta-Oxidation. Structure and Substrate Specificity of the Arabidopsis Thaliana Protein, Mfp2
Arent, S., Pye, V.E., Christen, C.E., Norgaard, A., Henriksen, A.
J.Biol.Chem. 285, pp. 24066 - Non-additivity of functional group contributions in protein-ligand binding: a comprehensive study by crystallography and isothermal titration calorimetry.
Baum, B., Muley, L., Smolinski, M., Heine, A., Hangauer, D., Klebe, G.
J.Mol.Biol. 397, pp. 1042 - Crystal Structure of Klebsiella Sp. Asr1 Phytase Suggests Substrate Binding to a Preformed Active Site that Meets the Requirements of a Plant Rhizosphere Enzyme.
Bohm, K., Herter, T., Mueller, J.J., Borriss, R., Heinemann, U.
FEBS J. 277, pp. 1284 - Congeneric but Still Distinct: How Closely Related Trypsin Ligands Exhibit Different Thermodynamic and Structural Properties
Brandt, T., Holzmann, N., Muley, L., Khayat, M., Wegscheid-Gerlach, C., Baum, B., Heine, A., Hangauer, D., Klebe, G.
J.Mol.Biol. , pp. - Crystal Structures of NodS N-Methyltransferase from Bradyrhizobium japonicum in Ligand-Free Form and as SAH Complex.
Cakici, O., Sikorski, M., Stepkowski, T., Bujacz, G., Jaskolski, M.
J.Mol.Biol. 404, pp. 874 - Structural Insight Into Substrate Differentiation of the Sugar-Metabolizing Enzyme Galactitol Dehydrogenase from Rhodobacter Sphaeroides D.
Carius, Y., Christian, H., Faust, A., Zander, U., Klink, B.U., Kornberger, P., Kohring, G.W., Giffhorn, F., Scheidig, A.J.
J.Biol.Chem. 285, pp. 20006 - Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus
Carrillo, D.R., Parthier, C., Janckel, N., Grandke, J., Stelter, M., Schilling, S., Boehme, M., Neumann, P., Wolf, R., Demuth, H.U., Stubbs, M.T., Rahfeld, J.U.
Biol.Chem. , pp. - Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein.
Dahms, S.O., Hoefgen, S., Roeser, D., Schlott, B., Guhrs, K.H., Than, M.E.
Proc.Natl.Acad.Sci.USA 107, pp. 5381 - Combining Crystallography and Molecular Dynamics: The Case of Schistosoma Mansoni Phospholipid Glutathione Peroxidase.
Dimastrogiovanni, D., Anselmi, M., Miele, A.E., Boumis, G., Petersson, L., Angelucci, F., Nola, A.D., Brunori, M., Bellelli, A.
Proteins 78, pp. 259 - Structural and functional characterization of CcmG from Pseudomonas aeruginosa, a key component of the bacterial cytochrome c maturation apparatus.
Di Matteo, A., Calosci, N., Gianni, S., Jemth, P., Brunori, M., Travaglini-Allocatelli, C.
Proteins 78, pp. 2213 - Fragment-Based Lead Discovery: Screening and Optimizing Fragments for Thermolysin Inhibition.
Englert, L., Silber, K., Steuber, H., Brass, S., Over, B., Gerber, H.D., Heine, A., Diederich, W.E., Klebe, G.
Chemmedchem 5, pp. 930 - Structural basis of oligomerization in the stalk region of dynamin-like MxA.
Gao, S., von der Malsburg, A., Paeschke, S., Behlke, J., Haller, O., Kochs, G., Daumke, O.
Nature 465, pp. 502 - Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Gunther, S., Schlundt, A., Sticht, J., Roske, Y., Heinemann, U., Wiesmuller, K.H., Jung, G., Falk, K., Rotzschke, O., Freund, C.
Proc.Natl.Acad.Sci.USA 107, pp. 22219 - The yeast E4 ubiquitin ligase Ufd2 interacts with the ubiquitin-like domains of Rad23 and Dsk2 via a novel and distinct ubiquitin-like binding domain.
Hanzelmann, P., Stingele, J., Hofmann, K., Schindelin, H., Raasi, S.
J.Biol.Chem. 285, pp. 20390 - Amyloid Fibril Recognition with the Conformational B10 Antibody Fragment Depends on Electrostatic Interactions.
Haupt, C., Morgado, I., Kumar, S.T., Parthier, C., Bereza, M., Hortschansky, P., Stubbs, M.T., Horn, U., Fandrich, M.
J.Mol.Biol. , pp. - Formation of the complex of nitrite with the ferriheme b beta-barrel proteins nitrophorin 4 and nitrophorin 7.
He, C., Ogata, H., Knipp, M.
Biochemistry 49, pp. 5841 - Structure of a Classical MHC Class I Molecule That Binds 'Non-Classical' Ligands.
Hee, C.S., Gao, S., Loll, B., Miller, M.M., Uchanska-Ziegler, B., Daumke, O., Ziegler, A.
Plos Biol. 8, pp. e1000557 - Structure of the Heme Biosynthetic Pseudomonas Aeruginosa Porphobilinogen Synthase in Complex with the Antibiotic Alaremycin.
Heinemann, I.U., Schulz, C., Schubert, W.D., Heinz, D.W., Wang, Y.G., Kobayashi, Y., Awa, Y., Wachi, M., Jahn, D., Jahn, M.
Antimicrob.Agents Chemother. 54, pp. 267 - Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin.
Hein, K.L., Kragh-Hansen, U., Morth, J.P., Jeppesen, M.D., Otzen, D., Moller, J.V., Nissen, P.
J.Struct.Biol. , pp. - Elimination of a cis-proline-containing loop and turn optimization stabilizes a protein and accelerates its folding.
Jakob, R.P., Zierer, B.K., Weininger, U., Hofmann, S.D., Lorenz, S.H., Balbach, J., Dobbek, H., Schmid, F.X.
J.Mol.Biol. 399, pp. 331 - Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth
Janiak, V., Petersen, M., Zentgraf, M., Klebe, G., Heine, A.
Acta Crystallogr.,Sect.D 66, pp. 593 - Crystal Structure of the ATP-Dependent Maturation Factor of Ni,Fe-Containing Carbon Monoxide Dehydrogenases
Jeoung, J.H., Giese, T., Grunwald, M., Dobbek, H.
J.Mol.Biol. 396, pp. 1165 - Molecular basis for association of PIPKI gamma-p90 with clathrin adaptor AP-2.
Kahlfeldt, N., Vahedi-Faridi, A., Koo, S.J., Schafer, J.G., Krainer, G., Keller, S., Saenger, W., Krauss, M., Haucke, V.
J.Biol.Chem. 285, pp. 2734 - Silver Ion Incorporation and Nanoparticle Formation Inside the Cavity of Pyrococcus Furiosus Ferritin: Structural and Size-Distribution Analyses.
Kasyutich, O., Ilari, A., Fiorillo, A., Tatchev, D., Hoell, A., Ceci, P.
J.Am.Chem.Soc. 132, pp. 3621 - Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases.
Kiliszek, A., Kierzek, R., Krzyzosiak, W.J., Rypniewski, W.
Nucleic Acids Res. 38, pp. 8370 - A coleopteran triosephosphate isomerase: X-ray structure and phylogenetic impact of insect sequences.
Knobeloch, D., Schmidt, A., Scheerer, P., Krauss, N., Wessner, H., Scholz, C., Kuttner, G., von Rintelen, T., Wessel, A., Hohne, W.
Insect Mol Biol 19, pp. 35 - Crystal structure of human cystatin C stabilized against amyloid formation.
Kolodziejczyk, R., Michalska, K., Hernandez-Santoyo, A., Wahlbom, M., Grubb, A., Jaskolski, M.
Febs J. 277, pp. 1726 - Crystal Structure of Hexokinase KlHxk1 of Kluyveromyces lactis: A MOLECULAR BASIS FOR UNDERSTANDING THE CONTROL OF YEAST HEXOKINASE FUNCTIONS VIA COVALENT MODIFICATION AND OLIGOMERIZATION.
Kuettner, E.B., Kettner, K., Keim, A., Svergun, D.I., Volke, D., Singer, D., Hoffmann, R., Muller, E.C., Otto, A., Kriegel, T.M., Strater, N.
J.Biol.Chem. 285, pp. 41019 - Thermodynamics and structure of a salmon cold-active goose-type lysozyme
Kyomuhendo, P., Myrnes, B., Brandsdal, B.O., Smalas, A.O., Nilsen, I.W., Helland, R.
Comp.Biochem.Physiol. B: Biochem.Mol.Biol. , pp. - Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA
Lakomek, K., Dickmanns, A., Ciirdaeva, E., Schomacher, L., Ficner, R.
J.Mol.Biol. 399, pp. 604 - Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for beta-D-galactopyranose
Licht, A., Bulut, H., Scheffel, F., Daumke, O., Wehmeier, U.F., Saenger, W., Schneider, E., Vahedi-Faridi, A.
J.Mol.Biol. , pp. - Crystal Structure Determination and Functional Characterization of the Metallochaperone SlyD from Thermus thermophilus
Loew, C., Neumann, P., Tidow, H., Weininger, U., Haupt, C., Friedrich-Epler, B., Scholz, C., Stubbs, M.T., Balbach, J.
J.Mol.Biol. 398, pp. 375 - Combination of two separate binding domains defines stoichiometry between type III secretion system chaperone IpgC and translocator protein IpaB
Lokareddy, R.K., Lunelli, M., Eilers, B., Wolter, V., Kolbe, M.
J.Biol.Chem. 285, pp. 39965 - Regulation and structure of YahD, a copper inducible alpha/beta hydrolase of Lactococcus lactis IL1403
Martinez, J., Mancini, S., Tauberger, E., Weise, C., Saenger, W., Solioz, M.
Fems Microbiol.Lett. , pp. - Crystal Structure of the P2 C-Repressor: A Binder of Non-Palindromic Direct DNA Repeats.
Massad, T., Skaar, K., Nilsson, H., Damberg, P., Henriksson-Peltola, P., Haggard-Ljungquist, E., Hogbom, M., Stenmark, P.
Nucleic Acids Res. 38, pp. 7778 - Double duty for a conserved glutamate in pyruvate decarboxylase: evidence of the participation in stereoelectronically controlled decarboxylation and in protonation of the nascent carbanion/enamine intermediate .
Meyer, D., Neumann, P., Parthier, C., Friedemann, R., Nemeria, N., Jordan, F., Tittmann, K.
Biochemistry 49, pp. 8197 - Crystal structure of Hyp-1, a St. John's wort protein implicated in the biosynthesis of hypericin
Michalska, K., Fernandes, H., Sikorski, M.M., Jaskolski, M.
J.Struct.Biol. 169, pp. 161 - Azole Drugs Trap Cytochrome P450 Eryk in Alternative Conformational States.
Montemiglio, L.C., Gianni, S., Vallone, B., Savino, C.
Biochemistry 49, pp. 9199 - The structures of mutant forms of Hfq from Pseudomonas aeruginosa reveal the importance of the conserved His57 for the protein hexamer organization.
Moskaleva, O., Melnik, B., Gabdulkhakov, A., Garber, M., Nikonov, S., Stolboushkina, E., Nikulin, A.
Acta Crystallogr.,Sect.F 66, pp. 760 - Evolution of CASK into a Mg2+-sensitive kinase.
Mukherjee, K., Sharma, M., Jahn, R., Wahl, M.C., Sudhof, T.C.
Sci.Signal. 3, pp. ra33 - Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates.
Ozga, M., Dolot, R., Janicka, M., Kaczmarek, R., Krakowiak, A.
J.Biol.Chem. 285, pp. 40809 - Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates.
Ozga, M., Dolot, R., Janicka, M., Kaczmarek, R., Krakowiak, A.
J.Biol.Chem. 285, pp. 40809 - The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells.
Patzke, C., Max, K.E., Behlke, J., Schreiber, J., Schmidt, H., Dorner, A.A., Kroger, S., Henning, M., Otto, A., Heinemann, U., Rathjen, F.G.
J.Neurosci. 30, pp. 2897 - Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2.
Pechstein, A., Bacetic, J., Vahedi-Faridi, A., Gromova, K., Sundborger, A., Tomlin, N., Krainer, G., Vorontsova, O., Schafer, J.G., Owe, S.G., Cousin, M.A., Saenger, W., Shupliakov, O., Haucke, V.
Proc.Natl.Acad.Sci.USA 107, pp. 4206 - Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2.
Pechstein, A., Bacetic, J., Vahedi-Faridi, A., Gromova, K., Sundborger, A., Tomlin, N., Krainer, G., Vorontsova, O., Schafer, J.G., Owe, S.G., Cousin, M.A., Saenger, W., Shupliakov, O., Haucke, V.
Proc.Natl.Acad.Sci.USA 107, pp. 4206 - Structure of Uracil-DNA N-Glycosylase (Ung) from Vibrio Cholerae. Mapping Temperature Adaptation Through Structural and Mutational Analysis.
Raeder, I.L.U., Moe, E., Willassen, N.P., Smalas, A.O., Leiros, I.
Acta Crystallogr.,Sect.F 66, pp. 130 - Molecular Basis for SH3 Domain Regulation of F-Bar-Mediated Membrane Deformation.
Rao, Y., Ma, Q., Vahedi-Faridi, A., Sundborger, A., Pechstein, A., Puchkov, D., Luo, L., Shupliakov, O., Saenger, W., Haucke, V.
Proc.Natl.Acad.Sci.USA 107, pp. 8213 - Insight Into the Induction Mechanism of the Gntr/Hutc Bacterial Transcription Regulator Yvoa
Resch, M., Schiltz, E., Titgemeyer, F., Muller, Y.A.
Nucleic Acids Res. 38, pp. 2485 - Synthesis of 5-hydroxyectoine from ectoine: crystal structure of the non-heme iron(II) and 2-oxoglutarate-dependent dioxygenase EctD
Reuter, K., Pittelkow, M., Bursy, J., Heine, A., Craan, T., Bremer, E.
Plos One 5, pp. e10647 - Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage.
Rychlik, M.P., Chon, H., Cerritelli, S.M., Klimek, P., Crouch, R.J., Nowotny, M.
Mol.Cell 40, pp. 658 - Insights into peroxisome function from the structure of PEX3 in complex with a soluble fragment of PEX19
Schmidt, F., Treiber, N., Zocher, G., Bjelic, S., Steinmetz, M.O., Kalbacher, H., Stehle, T., Dodt, G.
J.Biol.Chem. , pp. - Structural basis for the recognition and cleavage of polysialic acid by the bacteriophage K1F tailspike protein EndoNF.
Schulz, E.C., Schwarzer, D., Frank, M., Stummeyer, K., Muhlenhoff, M., Dickmanns, A., Gerardy-Schahn, R., Ficner, R.
J.Mol.Biol. 397, pp. 341 - Structural basis for the recognition and cleavage of polysialic acid by the bacteriophage K1F tailspike protein EndoNF.
Schulz, E.C., Schwarzer, D., Frank, M., Stummeyer, K., Muhlenhoff, M., Dickmanns, A., Gerardy-Schahn, R., Ficner, R.
J.Mol.Biol. 397, pp. 341 - Bidentate Zinc chelators for alpha-carbonic anhydrases that produce a trigonal bipyramidal coordination geometry.
Schulze Wischeler, J., Innocenti, A., Vullo, D., Agrawal, A., Cohen, S.M., Heine, A., Supuran, C.T., Klebe, G.
Chemmedchem 5, pp. 1609 - Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Schutz, P., Karlberg, T., van den Berg, S., Collins, R., Lehtio, L., Hogbom, M., Holmberg-Schiavone, L., Tempel, W., Park, H.W., Hammarstrom, M., Moche, M., Thorsell, A.G., Schuler, H.
Plos One 5, pp. 12791 - Structural Basis of Oligomerization in Septin-Like Gtpase of Immunity-Associated Protein 2 (Gimap2)
Schwefel, D., Froehlich, C., Eichhorst, J., Wiesner, B., Behlke, J., Aravind, L., Daumke, O.
Proc.Natl.Acad.Sci.USA 107, pp. 20299 - Mouse Apom Displays an Unprecedented Seven-Stranded Lipocalin Fold: Folding Decoy or Alternative Native Fold?
Sevvana, M., Kassler, K., Ahnstrom, J., Weiler, S., Dahlback, B., Sticht, H., Muller, Y.A.
J.Mol.Biol. 404, pp. 363 - Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif.
Siponen, M.I., Wisniewska, M., Lehtio, L., Johansson, I., Svensson, L., Raszewski, G., Nilsson, L., Sigvardsson, M., Berglund, H.
J.Biol.Chem. 285, pp. 25875 - Cysteine as a Modulator Residue in the Active Site of Xenobiotic Reductase A: A Structural, Thermodynamical and Kinetic Study
Spiegelhauer, O., Mende, S., Dickert, F., Knauer, S.H., Ullmann, G.M., Dobbek, H.
J.Mol.Biol. , pp. - Determinants of Substrate-Binding and-Protonation in the Flavoenzyme Xenobiotic Reductase A
Spiegelhauer, O., Werther, T., Mende, S., Knauer, S.H., Dobbek, H.
J.Mol.Biol. , pp. - The Crystal Structure of Ppil1 Bound to Cyclosporine a Suggests a Binding Mode for a Linear Epitope of the Skip Protein.
Stegmann, C.M., Luehrmann, R., Wahl, M.C.
Plos One 5, pp. 13 - Computational Design of a Chain-Specific Tetracycline Repressor Heterodimer.
Stiebritz, M.T., Wengrzik, S., Klein, D.L., Richter, J.P., Srebrzynski, A., Weiler, S., Muller, Y.A.
J.Mol.Biol. 403, pp. 371 - Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins
Treiber, N., Treiber, T., Zocher, G., Grosschedl, R.
Genes Dev. 24, pp. 2270 - Crystal Structures of the Solute Receptor GacH of Streptomyces glaucescens in Complex with Acarbose and an Acarbose Homolog: Comparison with the Acarbose-Loaded Maltose-Binding Protein of Salmonella typhimurium.
Vahedi-Faridi, A., Licht, A., Bulut, H., Scheffel, F., Keller, S., Wehmeier, U.F., Saenger, W., Schneider, E.
J.Mol.Biol. 397, pp. 709 - Structural Studies of Tri-Functional Human Gart.
Welin, M., Grossmann, J.G., Flodin, S., Nyman, T., Stenmark, P., Tresaugues, L., Kotenyova, T., Johansson, I., Nordlund, P., Lehtio, L.
Nucleic Acids Res. 38, pp. 7308 - Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface
Wenzel, S., Martins, B.M., Rosch, P., Wohrl, B.M.
Biochem.J. 425, pp. 373 - Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
Wisniewska, M., Karlberg, T., Lehtio, L., Johansson, I., Kotenyova, T., Moche, M., Schueler, H.
Plos One 5, pp. e8625 - Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
Wisniewska, M., Karlberg, T., Lehtio, L., Johansson, I., Kotenyova, T., Moche, M., Schuler, H.
Plos One 5, pp. e8625
2009
- Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects.
Angelucci, F., Sayed, A.A., Williams, D.L., Boumis, G., Brunori, M., Dimastrogiovanni, D., Miele, A.E., Pauly, F., Bellelli, A.
J.Biol.Chem. 284, pp. 28977 - Molecular Basis of Antimony Treatment in Leishmaniasis.
Baiocco, P., Colotti, G., Franceschini, S., Ilari, A.
J.Med.Chem. 52, pp. 2603 - Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin
Baum, B., Muley, L., Heine, A., Smolinski, M., Hangauer, D., Klebe, G.
J.Mol.Biol. 391, pp. 552 - The DEXD/H-box RNA Helicase DDX19 Is Regulated by an {alpha}-Helical Switch.
Collins, R., Karlberg, T., Lehtio, L., Schutz, P., van den Berg, S., Dahlgren, L.G., Hammarstrom, M., Weigelt, J., Schuler, H.
J.Biol.Chem. 284, pp. 10296 - Crystal structure of the shutoff and exonuclease protein from the oncogenic Kaposi's sarcoma-associated herpesvirus
Dahlroth, S.L., Gurmu, D., Schmitzberger, F., Engman, H., Haas, J., Erlandsen, H., Nordlund, P.
Febs J. 276, pp. 6636 - Structure and in vivo requirement of the yeast Spt6 SH2 domain
Dengl, S., Mayer, A., Sun, M., Cramer, P.
J.Mol.Biol. 389, pp. 211 - Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases
Federici, L., Lo Sterzo, C., Pezzola, S., Di Matteo, A., Scaloni, F., Federici, G., Caccuri, A.M.
Cancer Res. 69, pp. 8025 - Crystal structure of the antitoxin-toxin protein complex RelB-RelE from Methanococcus jannaschii
Francuski, D., Saenger, W.
J.Mol.Biol. 393, pp. 898 - Structure and function of primase RepB' encoded by broad-host-range plasmid RSF1010 that replicates exclusively in leading-strand mode
Geibel, S., Banchenko, S., Engel, M., Lanka, E., Saenger, W.
Proc.Natl.Acad.Sci.USA 106, pp. 7810 - Crystal structure of YnjE from Escherichia coli, a sulfurtransferase with three rhodanese domains.
Hanzelmann, P., Dahl, J.U., Kuper, J., Urban, A., Muller-Theissen, U., Leimkuhler, S., Schindelin, H.
Protein Sci. 18, pp. 2480 - The 1.4 A crystal structure of the large and cold-active Vibrio sp. alkaline phosphatase.
Helland, R., Larsen, R.L., Asgeirsson, B.
Biochim.Biophys.Acta 1794, pp. 297 - Crystal structures of g-type lysozyme from Atlantic cod shed new light on substrate binding and the catalytic mechanism.
Helland, R., Larsen, R.L., Finstad, S., Kyomuhendo, P., Larsen, A.N.
Cell.Mol.Life Sci. 66, pp. 2585 - Structural Basis of Enzymatic S-Norcoclaurine Biosynthesis.
Ilari, A., Franceschini, S., Bonamore, A., Arenghi, F., Botta, B., Macone, A., Pasquo, A., Bellucci, L., Boffi, A.
J.Biol.Chem. 284, pp. 897 - Structural basis of cyanide inhibition of Ni, Fe-containing carbon monoxide dehydrogenase
Jeoung, J.H., Dobbek, H.
J.Am.Chem.Soc. 131, pp. 9922 - Three-dimensional structure of N-terminal domain of DnaB helicase and helicase-primase interactions in Helicobacter pylori
Kashav, T., Nitharwal, R., Abdulrehman, S.A., Gabdoulkhakov, A., Saenger, W., Dhar, S.K., Gourinath, S.
Plos One 4, pp. e7515 - High-affinity recognition of lanthanide(III) chelate complexes by a reprogrammed human lipocalin 2.
Kim, H.J., Eichinger, A., Skerra, A.
J.Am.Chem.Soc. 131, pp. 3565 - Structural origins for selectivity and specificity in an engineered bacterial repressor-inducer pair.
Klieber, M.A., Scholz, O., Lochner, S., Gmeiner, P., Hillen, W., Muller, Y.A.
Febs J. 276, pp. 5610 - Crystal Structure of Kora Bound to Operator DNA: Insight Into Repressor Cooperation in Rp4 Gene Regulation
Koenig, B., Mueller, J.J., Lanka, E., Heinemann, U.
Nucleic Acids Res. 37, pp. 1915 - The high-resolution structure of the extracellular domain of human CD69 using a novel polymer
Kolenko, P., Skalova, T., Vanek, O., Stepankova, A., Duskova, J., Hasek, J., Bezouska, K., Dohnalek, J.
Acta Crystallogr.,Sect.F 65, pp. 1258 - Identification, structure, and functional requirement of the Mediator submodule Med7N/31
Koschubs, T., Seizl, M., Lariviere, L., Kurth, F., Baumli, S., Martin, D.E., Cramer, P.
Embo J. 28, pp. 69 - Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity.
Kotzsch, A., Nickel, J., Seher, A., Sebald, W., Muller, T.D.
Embo J. 28, pp. 937 - Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens
Kumar, P., Vahedi-Faridi, A., Saenger, W., Merino, E., Lopez de Castro, J.A., Uchanska-Ziegler, B., Ziegler, A.
J.Biol.Chem. 284, pp. 29784 - De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse
Lakomek, K., Dickmanns, A., Mueller, U., Kollmann, K., Deuschl, F., Berndt, A., Lubke, T., Ficner, R.
Acta Crystallogr.,Sect.D 65, pp. 220 - Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography
Lakomek, K., Dickmanns, A., Kettwig, M., Urlaub, H., Ficner, R., Luebke, T.
Bmc Struct.Biol. 9, pp. 56 - High-Resolution Crystal Structure of the Snake Venom Metalloproteinase Bap1 Complexed with a Peptidomimetic: Insight Into Inhibitor Binding.
Lingott, T.J., Schleberger, C., Gutierrez, J.M., Merfort, I.
Biochemistry 48, pp. 6166 - Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin
Luckner, S.R., Machutta, C.A., Tonge, P.J., Kisker, C.
Structure 17, pp. 1004 - IpaB-IpgC interaction defines binding motif for type III secretion translocator
Lunelli, M., Lokareddy, R.K., Zychlinsky, A., Kolbe, M.
Proc.Natl.Acad.Sci.USA 106, pp. 9661 - Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1.
Monecke, T., Dickmanns, A., Ficner, R.
Nucleic Acids Res. 37, pp. 3865 - Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP.
Monecke, T., Guttler, T., Neumann, P., Dickmanns, A., Gorlich, D., Ficner, R.
Science , pp. - The structure of Neuroglobin at high Xe and Kr pressure reveals partial conservation of globin internal cavities
Moschetti, T., Mueller, U., Schultze, J., Brunori, M., Vallone, B.
Biophys.J. 97, pp. 1700 - A C-terminal phosphatase module conserved in vertebrate CMP-sialic acid synthetases provides a tetramerization interface for the physiologically active enzyme.
Oschlies, M., Dickmanns, A., Haselhorst, T., Schaper, W., Stummeyer, K., Tiralongo, J., Weinhold, B., Gerardy-Schahn, R., von Itzstein, M., Ficner, R., Munster-Kuhnel, A.K.
J.Mol.Biol. 393, pp. 83 - Glyphosate resistance by engineering the flavoenzyme glycine oxidase.
Pedotti, M., Rosini, E., Molla, G., Moschetti, T., Savino, C., Vallone, B., Pollegioni, L.
J.Biol.Chem. , pp. - Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT
Ritschel, T., Hoertner, S., Heine, A., Diederich, F., Klebe, G.
Chembiochem 10, pp. 716 - How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA-Guanine Transglycosylase
Ritschel, T., Kohler, P.C., Neudert, G., Heine, A., Diederich, F., Klebe, G.
Chemmedchem 4, pp. 2012 - How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA-Guanine Transglycosylase
Ritschel, T., Kohler, P.C., Neudert, G., Heine, A., Diederich, F., Klebe, G.
Chemmedchem 4, pp. 2012 - An Integrative Approach Combining Noncovalent Mass Spectrometry, Enzyme Kinetics and X-ray Crystallography to Decipher Tgt Protein-Protein and Protein-RNA Interaction
Ritschel, T., Atmanene, C., Reuter, K., Van Dorsselaer, A., Sanglier-Cianferani, S., Klebe, G.
J.Mol.Biol. 393, pp. 833 - Structure and Function of the Abasic Site Specificity Pocket of an Ap Endonuclease from Archaeoglobus Fulgidus.
Schmiedel, R., Kuettner, E.B., Keim, A., Strater, N., Greiner-Stoffele, T.
DNA Repair 8, pp. 219 - Serendipitous Fatty Acid Binding Reveals the Structural Determinants for Ligand Recognition in Apolipoprotein M.
Sevvana, M., Ahnstrom, J., Egerer-Sieber, C., Lange, H.A., Dahlback, B., Muller, Y.A.
J.Mol.Biol. 393, pp. 920 - Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA.
Sokolowska, M., Czapinska, H., Bochtler, M.
Nucleic Acids Res. 37, pp. 3799 - Improving thermostability and catalytic activity of pyranose 2-oxidase from Trametes multicolor by rational and semi-rational design
Spadiut, O., Leitner, C., Salaheddin, C., Varga, B., Vertessy, B.G., Tan, T.C., Divne, C., Haltrich, D.
Febs J. 276, pp. 776 - Unusual Armadillo Fold in the Human General Vesicular Transport Factor P115
Striegl, H., Roske, Y., Kummel, D., Heinemann, U.
Plos One 4, pp. E4656 - Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S.
Sun, Q., Collins, R., Huang, S., Holmberg-Schiavone, L., Anand, G.S., Tan, C.H., van-den-Berg, S., Deng, L.W., Moore, P.K., Karlberg, T., Sivaraman, J.
J.Biol.Chem. 284, pp. 3076 - The Sars-Unique Domain (Sud) of Sars Coronavirus Contains Two Macrodomains that Bind G-Quadruplexes.
Tan, J., Vonrhein, C., Smart, O.S., Bricogne, G., Bollati, M., Kusov, Y., Hansen, G., Mesters, J.R., Schmidt, C.L., Hilgenfeld, R.
Plos Pathog. 5, pp. 428 - Dimer Formation of a Stabilized Gbeta1 Variant: A Structural and Energetic Analysis
Thoms, S., Max, K.E.A., Wunderlich, M., Jacso, T., Lilie, H., Reif, B., Heinemann, U., Schmid, F.X.
J.Mol.Biol. 391, pp. 918 - Role of a conserved active site cation-pi interaction in Escherichia coli serine hydroxymethyltransferase.
Vivoli, M., Angelucci, F., Ilari, A., Morea, V., Angelaccio, S., di Salvo, M.L., Contestabile, R.
Biochemistry 48, pp. 12034 - Structural Basis of the Cofactor- and Substrate-Assisted Activation of Human Coagulation Factor Ixa
Zogg, T., Brandstetter, H.
Structure 17, pp. 1669
2008
- Glutathione Reductase and Thioredoxin Reductase at the Crossroad: The Structure of Schistosoma Mansoni Thioredoxin Glutathione Reductase
Angelucci, F., Miele, A.E., Boumis, G., Dimastrogiovanni, D., Brunori, M., Bellelli, A.
Proteins 72, pp. 936 - Crystal Structure of Escherichia Coli Phage Hk620 Tailspike: Podoviral Tailspike Endoglycosidase Modules are Evolutionarily Related.
Barbirz, S., Mueller, J.J., Uetrecht, C., Clark, A.J., Heinemann, U., Seckler, R.
Mol.Microbiol. 69, pp. 303 - Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency.
Beich-Frandsen, M., Pickering, D.S., Mirza, O., Johansen, T.N., Greenwood, J., Vestergaard, B., Schousboe, A., Gajhede, M., Liljefors, T., Kastrup, J.S.
J.Med.Chem. 51, pp. 1459 - Structure-Guided Design of C2-Symmetric HIV-1 Protease Inhibitors Based on a Pyrrolidine Scaffold.
Blum, A., Bottcher, J., Heine, A., Klebe, G., Diederich, W.E.
J.Med.Chem. 51, pp. 2078 - Structural and Kinetic Analysis of Pyrrolidine-Based Inhibitors of the Drug-Resistant Ile84Val Mutant of HIV-1 Protease
Bottcher, J., Blum, A., Heine, A., Diederich, W.E., Klebe, G.
J.Mol.Biol. 383, pp. 347 - Demyelinating myelin oligodendrocyte glycoprotein-specific autoantibody response is focused on one dominant conformational epitope region in rodents
Breithaupt, C., Schafer, B., Pellkofer, H., Huber, R., Linington, C., Jacob, U.
J.Immunol. 181, pp. 1255 - Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
Brouns, S.J., Barends, T.R., Worm, P., Akerboom, J., Turnbull, A.P., Salmon, L., van der Oost, J.
J.Mol.Biol. 379, pp. 357 - The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site.
Chatwell, L., Holla, A., Kaufer, B.B., Skerra, A.
Mol.Immunol. 45, pp. 1981 - Designed Protein-Protein Association.
Grueninger, D., Treiber, N., Ziegler, M.O.P., Koetter, J.W.A., Schulze, M.-S., Schulz, G.E.
Science 319, pp. 206 - The Crystal Structure of the Protein Yhak from Escherichia Coli Reveals a New Subclass of Redox Sensitive Enterobacterial Bicupins.
Gurmu, D., Lu, J., Johnson, K.A., Nordlund, P., Holmgren, A., Erlandsen, H.
Proteins 74, pp. 18 - An Oxidized Tryptophan Facilitates Copper Binding in Methylococcus Capsulatus-Secreted Protein Mope.
Helland, R., Fjellbirkeland, A., Karlsen, O.A., Ve, T., Lillehaug, J.R., Jensen, H.B.
J.Biol.Chem. 283, pp. 13897 - Fab Mor03268 Triggers Absorption Shift of a Diagnostic Dye Via Packaging in a Solvent-Shielded Fab Dimer Interface
Hillig, R.C., Urlinger, S., Fanghanel, J., Brocks, B., Haenel, C., Stark, Y., Sulzle, D., Svergun, D.I., Baesler, S., Malawski, G., Moosmayer, D., Menrad, A., Schirner, M., Licha, K.
J.Mol.Biol. 377, pp. 206 - Biophysical Characterization of Refolded Drosophila Spatzle, a Cystine Knot Protein, Reveals Distinct Properties of Three Isoforms
Hoffmann, A., Funkner, A., Neumann, P., Juhnke, S., Walther, M., Schierhorn, A., Weininger, U., Balbach, J., Reuter, G., Stubbs, M.T.
J.Biol.Chem. 283, pp. 32598 - The X-Ray Structure of N-Methyltryptophan Oxidase Reveals the Structural Determinants of Substrate Specificity.
Ilari, A., Bonamore, A., Franceschini, S., Fiorillo, A., Boffi, A., Colotti, G.
Proteins 71, pp. 2065 - Structure of human argininosuccinate synthetase.
Karlberg, T., Collins, R., van den Berg, S., Flores, A., Hammarstrom, M., Hogbom, M., Holmberg Schiavone, L., Uppenberg, J.
Acta Crystallogr.,Sect.D 64, pp. 279 - Regulation of synaptic inhibition by phospho-dependent binding of the AP2 complex to a YECL motif in the GABAA receptor gamma2 subunit.
Kittler, J.T., Chen, G., Kukhtina, V., Vahedi-Faridi, A., Gu, Z., Tretter, V., Smith, K.R., McAinsh, K., Arancibia-Carcamo, I.L., Saenger, W., Haucke, V., Yan, Z., Moss, S.J.
Proc.Natl.Acad.Sci.Usa 105, pp. 3616 - High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp.
Kursula, P., Kursula, I., Massimi, M., Song, Y.H., Downer, J., Stanley, W.A., Witke, W., Wilmanns, M.
J.Mol.Biol. 375, pp. 270 - Zinc binding catalytic domain of human tankyrase 1.
Lehtio, L., Collins, R., van den Berg, S., Johansson, A., Dahlgren, L.G., Hammarstrom, M., Helleday, T., Holmberg-Schiavone, L., Karlberg, T., Weigelt, J.
J.Mol.Biol. 379, pp. 136 - Structural insights into an equilibrium folding intermediate of an archaeal ankyrin repeat protein
Loew, C., Weininger, U., Neumann, P., Klepsch, M., Lilie, H., Stubbs, M.T., Balbach, J.
Proc.Natl.Acad.Sci.Usa 105, pp. 3779 - Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode.
Monecke, T., Schell, S., Dickmanns, A., Ficner, R.
J.Mol.Biol. 382, pp. 827 - An Intersubunit Active Site between Supercoiled Parallel Beta Helices in the Trimeric Tailspike Endorhamnosidase of Shigella Flexneri Phage Sf6.
Muller, J.J., Barbirz, S., Heinle, K., Freiberg, A., Seckler, R., Heinemann, U.
Structure 16, pp. 766 - Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme pyruvate oxidase from Escherichia coli.
Neumann, P., Weidner, A., Pech, A., Stubbs, M.T., Tittmann, K.
Proc.Natl.Acad.Sci.USA 105, pp. 17390 - The Crystal Structure of the Human Toll-Like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer.
Nyman, T., Stenmark, P., Flodin, S., Johansson, I., Hammarstrom, M., Nordlund, P.
J.Biol.Chem. 283, pp. 11861 - Crystal structure of the ligand-free G-protein-coupled receptor opsin
Park, J.H., Scheerer, P., Hofmann, K.P., Choe, H.-W., Ernst, O.P.
Nature 454, pp. 183 - Structure and function of an RNase H domain at the heart of the spliceosome.
Pena, V., Rozov, A., Fabrizio, P., Luhrmann, R., Wahl, M.C.
Embo J. 27, pp. 2929 - Structure and function of an RNase H domain at the heart of the spliceosome.
Pena, V., Rozov, A., Fabrizio, P., Luhrmann, R., Wahl, M.C.
Embo J. 27, pp. 2929 - Crystal structure of trioxacarcin A covalently bound to DNA
Pfoh, R., Laatsch, H., Sheldrick, G.M.
Nucleic Acids Res. 36, pp. 3508 - Streptococcus pyogenes pSM19035 requires dynamic assembly of ATP-bound ParA and ParB on parS DNA during plasmid segregation.
Pratto, F., Cicek, A., Weihofen, W.A., Lurz, R., Saenger, W., Alonso, J.C.
Nucleic Acids Res. 36, pp. 3676 - Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Rossmann, M., Schultz-Heienbrok, R., Behlke, J., Remmel, N., Alings, C., Sandhoff, K., Saenger, W., Maier, T.
Structure 16, pp. 809 - Crystal structure of opsin in its G-protein-interacting conformation
Scheerer, P., Park, J.H., Hildebrand, P.W., Kim, Y.J., Krauss, N., Choe, H.-W., Hofmann, K.P., Ernst, O.P.
Nature 455, pp. 497 - The 1.8-A crystal structure of alpha1-acid glycoprotein (Orosomucoid) solved by UV RIP reveals the broad drug-binding activity of this human plasma lipocalin.
Schonfeld, D.L., Ravelli, R.B., Mueller, U., Skerra, A.
J.Mol.Biol. 384, pp. 393 - Structural and Functional Characterization of Human Iba Proteins.
Schulze, J.O., Quedenau, C., Roske, Y., Adam, T., Schuler, H., Behlke, J., Turnbull, A.P., Sievert, V., Scheich, C., Mueller, U., Heinemann, U., Bussow, K.
FEBS J. 275, pp. 4627 - Structural and Functional Characterization of Human Iba Proteins.
Schulze, J.O., Quedenau, C., Roske, Y., Adam, T., Schuler, H., Behlke, J., Turnbull, A.P., Sievert, V., Scheich, C., Mueller, U., Heinemann, U., Bussow, K.
FEBS J. 275, pp. 4627 - The Crystal Structure of Progesterone 5{Beta}-Reductase from Digitalis Lanata Defines a Novel Class of Short Chain Dehydrogenases/Reductases.
Thorn, A., Egerer-Sieber, C., Jaeger, C.M., Herl, V., Mueller-Uri, F., Kreis, W., Muller, Y.A.
J.Biol.Chem. 283, pp. 17260 - Structure and Mode of Action of a Mosquitocidal Holotoxin.
Treiber, N., Reinert, D.J., Carpusca, I., Aktories, K., Schulz, G.E.
J.Mol.Biol. 381, pp. 150 - The Crystal Structure of Human Cleavage and Polyadenylation Specific Factor-5 Reveals a Dimeric Nudix Protein with a Conserved Catalytic Site.
Tresaugues, L., Stenmark, P., Schuler, H., Flodin, S., Welin, M., Nyman, T., Hammarstrom, M., Moche, M., Graslund, S., Nordlund, P.
Proteins 73, pp. 1047 - Crystal structures and mutational analysis of the arginine-, lysine-, histidine-binding protein ArtJ from Geobacillus stearothermophilus. Implications for interactions of ArtJ with its cognate ATP-binding cassette transporter, Art(MP)2
Vahedi-Faridi, A., Eckey, V., Scheffel, F., Alings, C., Landmesser, H., Schneider, E., Saenger, W.
J.Mol.Biol. 375, pp. 448 - Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains
Yonus, H., Neumann, P., Zimmermann, S., May, J.J., Marahiel, M.A., Stubbs, M.T.
J.Biol.Chem. 283, pp. 32484 - Structural insight into signal conversion and inactivation by NTPDase2 in purinergic signaling
Zebisch, M., Strater, N.
Proc.Natl.Acad.Sci.Usa 105, pp. 6882 - Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding
Zhang, J.-L., Qiu, L.-Y., Kotzsch, A., Weidauer, S., Patterson, L., Hammerschmidt, M., Sebald, W., Mueller, T.D.
Dev.Cell 14, pp. 739 - A Putative Alpha-Helical Porin from Corynebacterium Glutamicum.
Ziegler, K., Benz, R., Schulz, G.E.
J.Mol.Biol. 379, pp. 482 - Conformational Changes and Reaction of Clostridial Glycosylating Toxins.
Ziegler, M.O.P., Jank, T., Aktories, K., Schulz, G.E.
J.Mol.Biol. 377, pp. 1346
2007
- Crystal Structure and Biochemical Properties of the d-Arabinose Dehydrogenase from Sulfolobus solfataricus
Brouns, S.J., Turnbull, A.P., Willemen, H.L., Akerboom, J., van der Oost, J.
J.Mol.Biol. 371, pp. 1249 - Understanding binding selectivity toward trypsin and factor Xa: the role of aromatic interactions
Di Fenza, A., Heine, A., Koert, U., Klebe, G.
Chemmedchem 2, pp. 297 - Affilin-Novel Binding Molecules Based on Human Gamma-B-Crystallin, an All Beta-Sheet Protein.
Ebersbach, H., Fiedler, E., Scheuermann, T., Fiedler, M., Stubbs, M.T., Reimann, C., Proetzel, G., Rudolph, R., Fiedler, U.
J.Mol.Biol. 372, pp. 172 - The Structure of a Bacterial L-Amino Acid Oxidase from Rhodococcus Opacus Gives New Evidence for the Hydride Mechanism for Dehydrogenation
Faust, A., Niefind, K., Hummel, W., Schomburg, D.
J.Mol.Biol. 367, pp. 234 - KNOBLE: a knowledge-based approach for the design and synthesis of readily accessible small-molecule chemical probes to test protein binding
Gerlach, C., Munzel, M., Baum, B., Gerber, H.-D., Craan, T., Diederich, W.E., Klebe, G.
Angew.Chem.Int.Ed.Engl. 46, pp. 9105 - Crystal Structure of the Electron Transfer Complex Rubredoxin - Rubredoxin Reductase from Pseudomonas Aeruginosa.
Hagelueken, G., Wiehlmann, L., Adams, T.M., Kolmar, H., Heinz, D.W., Tuemmler, B., Schubert, W.-D.
Proc.Natl.Acad.Sci.USA 104, pp. 12276 - Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.
Hald, H., Naur, P., Pickering, D.S., Sprogoe, D., Madsen, U., Timmermann, D.B., Ahring, P.K., Liljefors, T., Schousboe, A., Egebjerg, J., Gajhede, M., Kastrup, J.S.
J.Biol.Chem. 282, pp. 25726 - Corticosteroid-Binding Globulin: Structural Basis for Steroid Transport and Proteinase-Triggered Release
Klieber, M.A., Underhill, C., Hammond, G.L., Muller, Y.A.
J.Biol.Chem. 282, pp. 29594 - Structural Basis for Enzymatic Excision of N1-Methyladenine and N3-Methylcytosine from DNA
Leiros, I., Nabong, M.P., Grosvik, K., Ringvoll, J., Haugland, G.T., Uldal, L., Reite, K., Olsbu, I.K., Knaevelsrud, I., Moe, E., Andersen, O.A., Birkeland, N.K., Ruoff, P., Klungland, A., Bjelland, S.
Embo J. 26, pp. 2206 - How an agonist peptide mimics the antibiotic tetracycline to induce Tet-repressor
Luckner, S.R., Klotzsche, M., Berens, C., Hillen, W., Muller, Y.A.
J.Mol.Biol. 368, pp. 780 - Common mode of DNA binding to cold shock domains. Crystal structure of hexathymidine bound to the domain-swapped form of a major cold shock protein from Bacillus caldolyticus.
Max, K.E., Zeeb, M., Bienert, R., Balbach, J., Heinemann, U.
Febs J. 274, pp. 1265 - Optimized variants of the cold shock protein from in vitro selection: structural basis of their high thermostability.
Max, K.E., Wunderlich, M., Roske, Y., Schmid, F.X., Heinemann, U.
J.Mol.Biol. 369, pp. 1087 - Optimized variants of the cold shock protein from in vitro selection: structural basis of their high thermostability.
Max, K.E., Wunderlich, M., Roske, Y., Schmid, F.X., Heinemann, U.
J.Mol.Biol. 369, pp. 1087 - Ionotropic Glutamate-Like Receptor {Delta}2 Binds D-Serine and Glycine.
Naur, P., Hansen, K.B., Kristensen, A.S., Dravid, S.M., Pickering, D.S., Olsen, L., Vestergaard, B., Egebjerg, J., Gajhede, M., Traynelis, S.F., Kastrup, J.S.
Proc.Natl.Acad.Sci.USA 104, pp. 14116 - Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs.
Romir, J., Lilie, H., Egerer-Sieber, C., Bauer, F., Sticht, H., Muller, Y.A.
J.Mol.Biol. 365, pp. 1417 - Structural basis for catalytic activity and enzyme polymerization of phospholipid hydroperoxide glutathione peroxidase-4 (GPx4).
Scheerer, P., Borchert, A., Krauss, N., Wessner, H., Gerth, C., Hohne, W., Kuhn, H.
Biochemistry 46, pp. 9041 - Structure and Action of a Cc Bond Cleaving Alpha/Beta-Hydrolase Involved in Nicotine Degration.
Schleberger, C., Sachelaru, P., Brandsch, R., Schulz, G.E.
J.Mol.Biol. 367, pp. 409 - Crystal Structure of Human Inosine Triphosphatase. Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
Stenmark, P., Kursula, P., Flodin, S., Graslund, S., Landry, R., Nordlund, P., Schuler, H.
J.Biol.Chem. 282, pp. 3182 - Crystal structure of the anabaena sensory rhodopsin transducer.
Vogeley, L., Trivedi, V.D., Sineshchekov, O.A., Spudich, E.N., Spudich, J.L., Luecke, H.
J.Mol.Biol. 367, pp. 741 - Structural basis for RanGTP independent entry of spliceosomal U snRNPs into the nucleus.
Wohlwend, D., Strasser, A., Dickmanns, A., Ficner, R.
J.Mol.Biol. 374, pp. 1129 - Extending the host range of Listeria monocytogenes by rational protein design.
Wollert, T., Pasche, B., Rochon, M., Deppenmeier, S., van den Heuvel, J., Gruber, A.D., Heinz, D.W., Lengeling, A., Schubert, W.D.
Cell 129, pp. 891 - Extending the host range of Listeria monocytogenes by rational protein design.
Wollert, T., Pasche, B., Rochon, M., Deppenmeier, S., van den Heuvel, J., Gruber, A.D., Heinz, D.W., Lengeling, A., Schubert, W.D.
Cell 129, pp. 891 - Optimization of the gbeta1 domain by computational design and by in vitro evolution: structural and energetic basis of stabilization.
Wunderlich, M., Max, K.E., Roske, Y., Mueller, U., Heinemann, U., Schmid, F.X.
J.Mol.Biol. 373, pp. 775 - Structure and Action of the N-Oxygenase Aurf from Streptomyces Thioluteus.
Zocher, G.E., Winkler, R., Hertweck, C., Schulz, G.E.
J.Mol.Biol. 373, pp. 65
2006
- Serendipitous Sad Phasing of an Echinomycin-(Acgtacgt)2 Bisintercalation Complex.
Cuesta-Seijo, J.A., Weiss, M.S., Sheldrick, G.M.
Acta Crystallogr.,Sect.D 62, pp. 417 - Structure of the novel alpha-amylase AmyC from Thermotoga maritima.
Dickmanns, A., Ballschmiter, M., Liebl, W., Ficner, R.
Acta Crystallogr.,Sect.D 62, pp. 262 - Crystal Structures and Inhibitor Identification for Ptpn5, Ptprr and Ptpn7: A Family of Human Mapk- Specific Protein Tyrosine Phosphatases.
Eswaran, J., Von Kries, J.P., Marsden, B., Longman, E., Debreczeni, J.E., Ugochukwu, E., Turnbull, A., Lee, W.H., Knapp, S., Barr, A.J.
Biochem.J. 395, pp. 483 - Function and Structure of the Molybdenum Cofactor Carrier Protein from Chlamydomonas Reinhardtii.
Fischer, K., Llamas, A., Tejada-Jimenez, M., Schrader, N., Kuper, J., Ataya, F.S., Galvan, A., Mendel, R.R., Fernandez, E., Schwarz, G.
J.Biol.Chem. 281, pp. 30186 - The structure of bovine complement component 3 reveals the basis for thioester function.
Fredslund, F., Jenner, L., Husted, L.B., Nyborg, J., Andersen, G.R., Sottrup-Jensen, L.
J.Mol.Biol. 361, pp. 115 - Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Biochemistry 45, pp. 8243 - The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains.
Frese, S., Schubert, W.-D., Findeis, A.C., Marquardt, T., Roske, Y.S., Stradal, T.E.B., Heinz, D.W.
J.Biol.Chem. 281, pp. 18236 - Structure and Reaction Mechanism of L-Rhamnulose Kinase from Escherichia Coli.
Grueninger, D., Schulz, G.E.
J.Mol.Biol. 359, pp. 787 - Modulatory and Catalytic Modes of ATP Binding by the Calcium Pump
Jensen, A.M., Sorensen, T.L., Olesen, C., Moller, J.V., Nissen, P.
Embo J. 25, pp. 2305 - The crystal structure of the bacteriophage PSA endolysin reveals a unique fold responsible for specific recognition of Listeria cell walls
Korndoerfer, I.P., Danzer, J., Schmelcher, M., Zimmer, M., Skerra, A., Loessner, M.J.
J.Mol.Biol. 364, pp. 678 - Binding Structure of the Leucine Aminopeptidase Inhibitor Microginin Fr1.
Kraft, M., Schleberger, C., Weckesser, J., Schulz, G.E.
FEBS Lett. 580, pp. 6943 - Structure of the Bet3-Tpc6B Core of Trapp: Two Tpc6 Paralogs Form Trimeric Complexes with Bet3 and Mum2.
Kummel, D., Muller, J.J., Roske, Y., Henke, N., Heinemann, U.
J.Mol.Biol. 361, pp. 22 - Structures of the Hydrolase Domain of Human 10-Formyltetrahydrofolate Dehydrogenase and its Complex with a Substrate Analogue.
Kursula, P., Schuler, H., Flodin, S., Nilsson-Ehle, P., Ogg, D.J., Savitsky, P., Nordlund, P., Stenmark, P.
Acta Crystallogr.,Sect.D 62, pp. 1294 - Modulatory and Catalytic Modes of ATP Binding by the Calcium Pump
Lund Jensen, A.-M., Sorensen, T.L.-M., Olesen, C., Moller, J.V., Nissen, P.
Embo J. 25, pp. 2305 - Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold
Manjasetty, B.A., Buessow, K., Fieber-Erdmann, M., Roske, Y., Gobom, J., Scheich, C., Goetz, F., Niesen, F.H., Heinemann, U.
Protein Sci. 15, pp. 914 - T-rich DNA single strands bind to a preformed site on the bacterial cold shock protein Bs-CspB.
Max, K.E., Zeeb, M., Bienert, R., Balbach, J., Heinemann, U.
J.Mol.Biol. 360, pp. 702 - Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain.
Midtgaard, S.F., Assenholt, J., Jonstrup, A.T., Van, L.B., Jensen, T.H., Brodersen, D.E.
Proc.Natl.Acad.Sci.Usa 103, pp. 11898 - Structure and Action of the Binary C2 Toxin from Clostridium Botulinum.
Schleberger, C., Hochmann, H., Barth, H., Aktories, K., Schulz, G.E.
J.Mol.Biol. 364, pp. 705 - Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants.
Sevvana, M., Biadene, M., Ma, Q., Guo, C., Soling, H.-D., Sheldrick, G.M., Ferrari, D.M.
Acta Crystallogr.,Sect.D 62, pp. 589 - Natural Products as Starting Materials for Development of Second-Generation Serca Inhibitors Targeted Towards Prostate Cancer Cells
Soehoel, H., Jensen, A.L., Moller, J.V., Nissen, P., Denmeade, S.R., Isaacs, J.T., Olsen, C.E., Christensen, S.B.
Bioorg.Med.Chem. 14, pp. 2810 - The Crystal Structure of Arabidopsis Thaliana Rac7/Rop9: The First Ras Superfamily Gtpase from the Plant Kingdom.
Sormo, C.G., Leiros, I., Brembu, T., Winge, P., Os, V., Bones, A.M.
Phytochemistry 67, pp. 2332 - Recognition of a Functional Peroxisome Type 1 Target by the Dynamic Import Receptor Pex5P.
Stanley, W.A., Filipp, F.V., Kursula, P., Schuller, N., Erdmann, R., Schliebs, W., Sattler, M., Wilmanns, M.
Mol.Cell 24, pp. 653 - High-resolution crystal structure of aldose reductase complexed with the novel sulfonyl-pyridazinone inhibitor exhibiting an alternative active site anchoring group.
Steuber, H., Zentgraf, M., Podjarny, A., Heine, A., Klebe, G.
J.Mol.Biol. 356, pp. 45 - Structures of Omega Repressors Bound to Direct and Inverted DNA Repeats Explain Modulation of Transcription.
Weihofen, W.A., Cicek, A., Pratto, F., Alonso, J.C., Saenger, W.
Nucleic Acids Res. 34, pp. 1450
2005
- Crystal Structure of 5-Aminolevulinate Synthase, the First Enzyme of Heme Biosynthesis, and its Link to Xlsa in Humans.
Astner, I., Schulze, J.O., Van Den Heuvel, J.J., Jahn, D., Schubert, W.-D., Heinz, D.W.
Embo J. 24, pp. 3166 - High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide.
Blicher, T., Kastrup, J.S., Buus, S., Gajhede, M.
Acta Crystallogr.,Sect.D 61, pp. 1031 - Engineering a selectable marker for hyperthermophiles
Brouns, S.J.J., Wu, H., Akerboom, J., Turnbull, A.P., de Vos, W.M., van der Oost, J.
J.Biol.Chem. 280, pp. 11422 - Structure of the Lipopeptide Antibiotic Tsushimycin.
Bunkoczi, G., Vertesy, L., Sheldrick, G.M.
Acta Crystallogr.,Sect.D 61, pp. 1160 - The Antiviral Antibiotic Feglymycin: First Direct Methods Solution of a 1000Plus Equal-Atom Structure
Bunkoczi, G., Vertesy, L., Sheldrick, G.M.
Angew.Chem.Int.Ed.Engl. 44, pp. 1340 - Crystal Structure of Yersinia Enterocolitica Type III Secretion Chaperone Syct.
Buttner, C.R., Cornelis, G.R., Heinz, D.W., Niemann, H.H.
Protein Sci. 14, pp. 1993 - Structures of Complexes between Echinomycin and Duplex DNA.
Cuesta-Seijo, J.A., Sheldrick, G.M.
Acta Crystallogr.,Sect.D 61, pp. 442 - Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination.
Dong, C., Flecks, S., Unversucht, S., Haupt, C., van Pee, K.H., Naismith, J.H.
Science 309, pp. 2216 - High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability.
Eisenberg-Domovich, Y., Hytonen, V.P., Wilchek, M., Bayer, E.A., Kulomaa, M.S., Livnah, O.
Acta Crystallogr.,Sect.D 61, pp. 528 - The Mutation G145S in Prfa, a Key Virulence Regulator of Listeria Monocytogenes, Increases DNA-Binding Affinity by Stabilizing the Hth Motif
Eiting, M., Hagelueken, G., Schubert, W.-D., Heinz, D.W.
Mol.Microbiol. 56, pp. 433 - Allele-Dependent Similarity between Viral and Self-Peptide Presentation by Hla-B27 Subtypes
Fiorillo, M.T., Ruckert, C., Hulsmeyer, M., Sorrentino, R., Saenger, W., Ziegler, A., Uchanska-Ziegler, B.
J.Biol.Chem. 280, pp. 2962 - High Resolution Crystal Structures of Human Rab4A in its Active and Inactive Conformations.
Huber, S.K., Scheidig, A.J.
FEBS Lett. 579, pp. 2821 - Thermodynamic and Structural Equivalence of Two Hla-B27 Subtypes Complexed with a Self-Peptide
Hulsmeyer, M., Welfle, K., Pohlmann, T., Misselwitz, R., Alexiev, U., Welfle, H., Saenger, W., Uchanska-Ziegler, B., Ziegler, A.
J.Mol.Biol. 346, pp. 1367 - Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry.
Joergensen, R., Merrill, A.R., Yates, S.P., Marquez, V.E., Schwan, A.L., Boesen, T., Andersen, G.R.
Nature 436, pp. 979 - Structure of Ecballium Elaterium Trypsin Inhibitor II (Eeti-II): A Rigid Molecular Scaffold
Kraetzner, R., Debreczeni, J.E., Pape, T., Schneider, T.R., Wentzel, A., Kolmar, H., Scheldrick, G.M., Uson, I.
Acta Crystallogr.,Sect.D 61, pp. 1255 - The Structure of the Trapp Subunit Tpc6 Suggests a Model for a Trapp Subcomplex.
Kummel, D., Mueller, J.J., Roske, Y., Misselwitz, R., Bussow, K., Heinemann, U.
Embo Rep. 6, pp. 787 - X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1)
Manjasetty, B.A., Niesen, F.H., Scheich, C., Roske, Y., Gotz, F., Behlke, J., Sievert, V., Heinemann, U., Bussow, K.
Bmc Struct.Biol. 5, pp. 21 - Succinate Complex Crystal Structures of the Alpha-Ketoglutarate-Dependent Dioxygenase Atsk: Steric Aspects of Enzyme Self-Hydroxylation
Mueller, I., Stueckl, A.C., Wakeley, J., Kertesz, M., Uson, I.
J.Biol.Chem. 280, pp. 5716 - Succinate Complex Crystal Structures of the Alpha-Ketoglutarate-Dependent Dioxygenase Atsk: Steric Aspects of Enzyme Self-Hydroxylation
Mueller, I., Stueckl, A.C., Wakeley, J., Kertesz, M., Uson, I.
J.Biol.Chem. 280, pp. 5716 - Structure of the unphosphorylated STAT5a dimer
Neculai, D., Neculai, A.M., Verrier, S., Straub, K., Klumpp, K., Pfitzner, E., Becker, S.
J.Biol.Chem. 280, pp. 40782 - De novo calcium/sulfur SAD phasing of the human formylglycine-generating enzyme using in-house data.
Roeser, D., Dickmanns, A., Gasow, K., Rudolph, M.G.
Acta Crystallogr.,Sect.D 61, pp. 1057 - Conjugated Bile Acid Hydrolase is a Tetrameric N-Terminal Thiol Hydrolase with Specific Recognition of its Cholyl But not of its Tauryl Product
Rossocha, M., Schultz-Heienbrok, R., Von Moeller, H., Coleman, J.P., Saenger, W.
Biochemistry 44, pp. 5739 - An Old Target Revisited: Two New Privileged Skeletons and an Unexpected Binding Mode For HIV-Protease Inhibitors
Specker, E., Boettcher, J., Lilie, H., Heine, A., Schoop, A., Muller, G., Griebenow, N., Klebe, G.
Angew.Chem.Int.Ed.Engl. 44, pp. 3140 - The crystal structure of archaeal nascent polypeptide-associated complex (NAC) reveals a unique fold and the presence of a UBA domain
Spreter, T., Pech, M., Beatrix, B.
J.Biol.Chem. 280, pp. 15849 - Structural basis for m(3)G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1
Strasser, A., Dickmanns, A., Luehrmann, R., Ficner, R.
Embo J. 24, pp. 2235 - Crystal Structure of the Polysialic Acid-Degrading Endosialidase of Bacteriophage K1F
Stummeyer, K., Dickmanns, A., Muehlenhoff, M., Gerardy-Schahn, R., Ficner, R.
Nat.Struct.Mol.Biol. 12, pp. 90 - Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization
Turnbull, A.P., Prinz, B., Holz, C., Schultchen, J., Lang, C.
Embo J. 24, pp. 875 - Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase
Wallden, K., Ruzzenente, B., Rinaldo-Matthis, A., Bianchi, V., Nordlund, P.
STRUCTURE 13, pp. 1081
2004
- Structural Basis of Redox-coupled Protein Substrate Selection by the Cytochrome c Biosynthesis Protein ResA.
Crow, A., Acheson, R.M., Le Brun, N.E., Oubrie, A.
J.Biol.Chem. 279, pp. 23654 - X-ray structure of tRNA pseudouridine synthase TruD reveals an inserted domain with a novel fold
Ericsson, U.B., Nordlund, P., Hallberg, B.M.
Febs Lett. 565, pp. 59 - Dual, Hla-B27 Subtype-Dependent Conformation of a Self-Peptide
Hulsmeyer, M., Fiorillo, M.T., Bettosini, F., Sorrentino, R., Saenger, W., Ziegler, A., Uchanska-Ziegler, B.
J.Exp.Med. 199, pp. 271 - Sequence-specific DNA binding determined by contacts outside the helix-turn-helix motif of the ParB homolog KorB.
Khare, D., Ziegelin, G., Lanka, E., Heinemann, U.
Nat.Struct.Mol.Biol. 11, pp. 656 - Crystal structure of Homo sapiens protein hp14.5.
Manjasetty, B.A., Delbruck, H., Pham, D.T., Mueller, U., Fieber-Erdmann, M., Scheich, C., Sievert, V., Bussow, K., Niesen, F.H., Weihofen, W., Loll, B., Saenger, W., Heinemann, U., Neisen, F.H.
Proteins 54, pp. 797 - X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma.
Manjasetty, B.A., Quedenau, C., Sievert, V., Buessow, K., Niesen, F., Delbrueck, H., Heinemann, U.
Proteins 55, pp. 214 - X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880.
Manjasetty, B.A., Niesen, F.H., Delbruck, H., Gotz, F., Sievert, V., Bussow, K., Behlke, J., Heinemann, U.
Biol.Chem. 385, pp. 935 - Latent LytM at 1.3A resolution.
Odintsov, S.G., Sabala, I., Marcyjaniak, M., Bochtler, M.
J.Mol.Biol. 335, pp. 775 - Crystal Structure of the 65-Kilodalton Heat Shock Protein, Chaperonin 60.2, of Mycobacterium tuberculosis
Qamra, R., Mande, S.C.
J.Bacteriol. 186, pp. 8105 - High-resolution crystal structures of Caldicellulosiruptor strain Rt8B.4 carbohydrate-binding module CBM27-1 and its complex with mannohexaose.
Roske, Y., Sunna, A., Pfeil, W., Heinemann, U.
J.Mol.Biol. 340, pp. 543 - High-resolution crystal structures of Caldicellulosiruptor strain Rt8B.4 carbohydrate-binding module CBM27-1 and its complex with mannohexaose.
Roske, Y., Sunna, A., Pfeil, W., Heinemann, U.
J.Mol.Biol. 340, pp. 543 - Structural Insights into the Neuroprotective-acting Carbonyl Reductase Sniffer of Drosophila melanogaster.
Sgraja, T., Ulschmid, J., Becker, K., Schneuwly, S., Klebe, G., Reuter, K., Heine, A.
J.Mol.Biol. 342, pp. 1613 - Phosphoryl transfer and calcium ion occlusion in the calcium pump.
Sorensen, T.L., Moller, J.V., Nissen, P.
Science 304, pp. 1672 - Phosphoryl transfer and calcium ion occlusion in the calcium pump.
Sorensen, T.L.-M., Moller, J.V., Nissen, P.
Science 304, pp. 1672 - Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis.
Sprogoe, D., van den Broek, L.A., Mirza, O., Kastrup, J.S., Voragen, A.G., Gajhede, M., Skov, L.K.
Biochemistry 43, pp. 1156 - Crystal Structure of CaiB, a Type-III CoA Transferase in Carnitine Metabolism
Stenmark, P., Gurmu, D., Nordlund, P.
Biochemistry 43, pp. 13996 - Anabaena sensory rhodopsin: a photochromic color sensor at 2.0 A.
Vogeley, L., Sineshchekov, O.A., Trivedi, V.D., Sasaki, J., Spudich, J.L., Luecke, H.
Science 306, pp. 1390 - Crystal Structure of Cd26/Dipeptidyl-Peptidase Iv in Complex with Adenosine Deaminase Reveals a Highly Amphiphilic Interface
Weihofen, W.A., Liu, J., Reutter, W., Saenger, W., Fan, H.
J.Biol.Chem. 279, pp. 43330
2003
- Crystal Structure of Coproporphyrinogen III Oxidase Reveals Cofactor Geometry of Radical Sam Enzymes
Layer, G., Moser, J., Heinz, D.W., Jahn, D., Schubert, W.-D.
Embo J. 22, pp. 6214 - Structure of DNA helicase RepA in complex with sulfate at 1.95 A resolution implicates structural changes to an 'open' form.
Xu, H., Strater, N., Schroder, W., Bottcher, C., Ludwig, K., Saenger, W.
Acta Crystallogr.,Sect.D 59, pp. 815
