Large area graphene based biosensor

Sensing of biomolecules

Large-area graphene based sensor

Graphene is a conducting substrate that can be functionalized homogeneously [6,7] and transferred to any other material conducting or non-conducting without any remarkable loss of functionality [7].

Fig. 7: Top: Sketch of the surface functionalization of graphene by maleimido-phenyl (MP) via electrochemical reduction of p-Maleimidobenzene-tetrafluoroborate. Bottom: Functionalization of graphene on copper and subsequent transfer on another substrate (here oxidized Si wafer).

Fig. 8: Raman spectra of a) unmodified graphene (Gr) transferred on glass, b) maleimidophenyl (MP) functionalized graphene on copper; MP/Gr transferred to c) thick SiO2 layer on Si, to d) Au/Si and to e) PTFE foil. The spectra are shifted vertically for clarity. The * marked bands are due to PTFE. Excitation with 488 nm.


references

[6] Quantifying the electrochemical maleimidation of large area graphene; Rösicke, F.; Gluba, M.A.; Hinrichs, K.; Sun, G.; Nickel, N.H.; Rappich, J.; Electrochem. commun. 57 (2015) 52.

[7] Functionalization of any substrate using covalently modified large area CVD graphene; Rösicke, F.; Gluba, M.A.; Shaykhutdinov, T.; Sun, G.; Kratz, C.; Rappich, J.; Hinrichs, K.; Nickel, N.H.; Chem. Commun. 53 (2017) 9308.