Structure of the month - June 2014

Overall structure of Ty3 RT in complex with an RNA/DNA hybrid. The polymerase subdomains are colored blue, red and green and the RNase H domains in yellow. Lighter shades of the colors are used for the subunit with altered conformation and blocked polymerase active site. The RNA strand of the hybrid is in purple and the DNA strand in marine. Active site residues are shown as sticks.

Table 1.