Beltrán, A. M.; Civantos, A.; Dominguez-Trujillo, C.; Moriche, R.; Rodriguez-Ortiz, J.A.; Garcia-Moreno, F.; Webster, T.J.; Kamm, P. H.; Mesa Restrepo, A.; Torres, Y.: Porous Titanium Surfaces to Control Bacteria Growth: Mechanical Properties and Sulfonated Polyetheretherketone Coatings as Antibiofouling Approaches. Metals 9 (2019), p. 995/1-18
10.3390/met9090995
Open Accesn Version

Abstract:
Here, titanium porous substrates were fabricated by a space holder technique. The relationship between microstructural characteristics (pore equivalent diameter, mean free-path between pores, roughness and contact surface), mechanical properties (Young’s modulus, yield strength and dynamic micro-hardness) and bacterial behavior are discussed. The bacterial strains evaluated are often found on dental implants: Methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. The colony-forming units increased with the size of the spacer for both types of studied strains. An antibiofouling synthetic coating based on a sulfonated polyetheretherketone polymer revealed an e ective chemical surface modification for inhibiting MRSA adhesion and growth. These findings collectively suggest that porous titanium implants designed with a pore size of 100–200 m can be considered most suitable, assuring the best biomechanical and bifunctional anti-bacterial properties.