Delajon, C.; Gutberlet, T.; Steitz, R.; Möhwald, H.; Krastev, R.: Formation of polyelectrolyte multilayer architectures with embedded DMPC studied in situ by neutron reflectometry. Langmuir 21 (2005), p. 8509-8514
10.1021/la050407n
Abstract:
The coupling of lipid molecules to polymer components in a planar biomimetic model membrane made of a lipid bilayer (dimyristoylphosphatidylcholine) supported by polyelectrolyte multilayers is studied. The polyelectrolyte support was prepared by layer-by-layer deposition of positively charged poly(allylamine hydrochloride) (PAH) and negatively charged poly(sodium 4-styrenesulfonate) (PSS). Two polymer sample terminations were considered: positively charged (PAH-terminated) and negatively charged (PSS-terminated). Neutron reflectometry studies showed that, whereas positively charged samples did not favor the deposition of lipid, negatively charged samples allowed the deposition of a lipid bilayer with a thickness of ?5 nm. In the latter case, formation of polyelectrolyte layers after the deposition of the lipid layer was also possible. © 2005 American Chemical Society.