Hagen, C.; Dent, K.C.; Zeev-Ben-Mordehai, T.; Grange, M.; Bosse, J.B.; Whittle, C.; Klupp, B.G.; Siebert, C.A.; Vasishtan, D.; Baeuerlein, F.J.B.; Cheleski, J.; Werner, S.; Guttmann, P.; Rehbein, S.; Henzler, K.; Demmerle, J.; Adler, B.; Koszinowski, U.; Schermelleh, L.; Schneider, G.; Enquist, L.W.; Plitzko, J.M.; Mettenleiter, T.C.; Gruenewald, K.: Structural Basis of Vesicle Formation at the Inner Nuclear Membrane. Cell 163 (2015), p. 1692-1701
10.1016/j.cell.2015.11.029
Open Access Version (externer Anbieter)
Abstract:
A multi-modal live-cell and cryo-imaging approach reveals how vesicles assemble at the inner nuclear membrane for transport to the cytoplasm during herpesvirus maturation. This also suggests a functional model for counterparts in uninfected cells that mediate nuclear egress of large cargo like ribonucleoprotein particles.