MX 14.2
MX_BEAMLINE_14.2
Publikationen
2024Scheuerer, S.; Motlova, L.; Schäker-Hübner, L.; Sellmer, A.; Feller, F.; Ertl, F.J.; Koch, P.; Hansen, F.K.; Barinka, C.; Mahboobi, S.: Biological and structural investigation of tetrahydro-β-carboline-based selective HDAC6 inhibitors with improved stability. , European Journal of Medicinal Chemistry 276 (2024), p. 116676/1-11
doi: 10.1016/j.ejmech.2024.116676
Voget, R.; Breidenbach, J.; Claff, T.; Hingst, A.; Sylvester, K.; Steinebach, C.; Vu, L. P.; Weisse, R.H.; Bartz, U.; Straeter, N.; Mueller, C.E.; Guetschow, M.: Development of an active-site titrant for SARS-CoV-2 main protease as an indispensable tool for evaluating enzyme kinetics. , Acta Pharmaceutica Sinica B 14 (2024), p. 2349-2357
doi: 10.1016/j.apsb.2024.03.001
Novakova, Z.; Tehrani, Z.A.; Jurok, R.; Motlova, L.; Kutil, Z.; Pavlicek, J.; Shukla, S.; Choy, C.J.; Havlinova, B.; Baranova, P.; Berkman, C.E.; Kuchar, M.; Cerny, J.; Barinka, C.: Structural, Biochemical, and Computational Characterization of Sulfamides as Bimetallic Peptidase Inhibitors. , Journal of Chemical Information and Modeling 64 (2024), p. 1030–1042
doi: 10.1021/acs.jcim.3c01542
Buffa, V.; Meyners, C.; Sugiarto, W.O.; Bauder, M.; Gaali, S.; Hausch, F.: 1,4-Pyrazolyl-Containing SAFit-Analogues are Selective FKBP51 Inhibitors With Improved Ligand Efficiency and Drug-Like Profile. , ChemMedChem 19 (2024), p. e202400264/1-23
doi: 10.1002/cmdc.202400264
2023
Grabicki, Niklas Jan: Curved Carbon Materials : Strained Macrocycles and Photomagnetic Switches. , HU Berlin, Dissertation, 2023
doi: 10.18452/26967
Burmeister, David: Exploring graphitic carbon nitrides for (opto)electronic applications. , HU Berlin , 2023
Abylgazina, Leila: Stimuli-induced structural switchability in the pillared-layer metal-organic framework DUT-8. , TU Dresden, 2023
Dimos, Nicole: Structural and biochemical characterization of biotechnologically relevant enzymes. , FU Berlin, 2023
Felsner, Bodo: Synthese von DUT-13 und isoretikulären MOFs und Untersuchung ihrer adsorptionsinduzierten Flexibilität. , TU Dresden, 2023
Khilji, Sana Khan: The development of antibodies against tumour-associated carbohydrate antigens. , FU Berlin, 2023
Fanfrlík, J.; Brynda, J.; Kugler, M.; Lepsik, M.; Pospísilová, K.; Holub, J.; Hnyk, D.; Nekvinda, J.; Grüner, B.; Rezácová, P.: B–H⋯π and C–H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides. , Physical Chemistry Chemical Physics 25 (2023), p. 1728-1733
doi: 10.1039/d2cp04673c
Kascakova, B.; Kotal, J.; Havlickova, P.; Vopatkova, V.; Prudnikova, T.; Grinkevich, P.; Kuty, M.; Chmelar, J.; Kuta Smatanova, I.: Conformational transition of the Ixodes ricinus salivary serpin Iripin-4. , Acta Crystallographica Section D - Structural biology 79 (2023), p. 409-419
doi: 10.1107/s2059798323002322
Svoboda, J.; Berdar, D.; Kolenko, P.; Cerny, J.; Novakova, Z.; Pavlicek, J.; Schneider, B.: Conformation-based refinement of 18-mer DNA structures. , Acta Crystallographica Section D - Structural biology 79 (2023), p. 655-665
doi: 10.1107/s2059798323004679
Magoch, M.; McEwen, A.G.; Napolitano, V.; Wladyka, B.; Dubin, G.: Crystal Structure of Staphopain C from Staphylococcus aureus. , Molecules (Basel) 28 (2023), p. 4407/1-10
doi: 10.3390/molecules28114407
Eisenreichova, A.; Klima, M.; Anila, M.M.; Koukalova, A.; Humpolickova, J.; Rozycki, B.; Boura, E.: Crystal Structure of the ORP8 Lipid Transport ORD Domain: Model of Lipid Transport. , Cells 12 (2023), p. 1974/1-13
doi: 10.3390/cells12151974
Werten, S.; Waack, P.; Palm, G.J.; Virolle, M.J.; Hinrichs, W.: Crystal structures of free and ligand-bound forms of the TetR/AcrR-like regulator SCO3201 from Streptomyces coelicolor suggest a novel allosteric mechanism. , FEBS Journal 290 (2023), p. 521-532
doi: 10.1111/febs.16606
Kremling, V.; Loll, B.; Pach, S.; Dahmani, I.; Weise, C.; Wolber, G.; Chiantia, S.; Wahl, M.C.; Osterrieder, N.; Azab, W.: Crystal structures of glycoprotein D of equine alphaherpesviruses reveal potential binding sites to the entry receptor MHC-I. , Frontiers in Microbiology 14 (2023), p. 1197120/1-16
doi: 10.3389/fmicb.2023.1197120
Gardonyi, M.; Hasewinkel, C.; Wallbaum, J.; Wollenhaupt, J.; Weiss, M.S.; Klebe, G.; Reuter, K.; Heine, A.: Crystallographic Fragment Screening on the Shigella Type III Secretion System Chaperone IpgC. , ACS Omega 8 (2023), p. 46051-46065
doi: 10.1021/acsomega.3c07058
Purder, P.L.; Meyners, C.; Sugiarto, W.O.; Kolos, J.; Lohr, F.; Gebel, J.; Nehls, T.; Dotsch, V.; Lermyte, F.; Hausch, F.: Deconstructing Protein Binding of Sulfonamides and Sulfonamide Analogues. , JACS Au : an open access journal of the American Chemical Society 3 (2023), p. 2478-2486
doi: 10.1021/jacsau.3c00241
Orsi, D.L.; Ferrara, S.J.; Siegel, S.; Friberg, A.; Bouche, L.; Pook, E.; Lienau, P.; Bluck, J.P.; Lemke, C.T.; Akcay, G.; Stellfeld, T.; Meyer, H.; Putter, V.; Holton, S.J.; Korr, D.; Jerchel-Furau, I.; Pantelidou, C.; Strathdee, C.A.; Meyerson, M.; Eis, K.; Goldstein, J.T.: Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists. , Bioorganic & Medicinal Chemistry 78 (2023), p. 117130/1-14
doi: 10.1016/j.bmc.2022.117130
Geiger, T.M.; Walz, M.; Meyners, C.; Kuehn, A.; Dreizler, J.K.; Sugiarto, W.O.; Maciel, E.; Zheng, M.; Lermyte, F.; Hausch, F.: Discovery of a Potent PROTAC Enables Targeting of FKBP51's Scaffolding Functions. , Angewandte Chemie - International Edition 63 (2023), p. e202309706/1-7
doi: 10.1002/anie.202309706
Schnepel, C.; Moritzer, A.C.; Gafe, S.; Montua, N.; Minges, H.; Niess, A.; Niemann, H.H.; Sewald, N.: Enzymatic Late-Stage Halogenation of Peptides. , ChemBioChem 24 (2023), p. e202200569/1-9
doi: 10.1002/cbic.202200569
Saathoff, M.; Kosol, S.; Semmler, T.; Tedin, K.; Dimos, N.; Kupke, J.; Seidel, M.; Ghazisaeedi, F.; Jonske, M.C.; Wolf, S.A.; Kuropka, B.; Czyszczon, W.; Ghilarov, D.; Gratz, S.; Heddle, J.G.; Loll, B.; Sussmuth, R.D.; Fulde, M.: Gene amplifications cause high-level resistance against albicidin in gram-negative bacteria. , PLoS Biology 21 (2023), p. e3002186/1-18
doi: 10.1371/journal.pbio.3002186
Kugler, M.; Hadzima, M.; Dzijak, R.; Rampmaier, R.; Srb, P.; Vrzal, L.; Voburka, Z.; Majer, P.; Rezacova, P.; Vrabel, M.: Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study. , RSC Medicinal Chemistry 14 (2023), p. 144-153
doi: 10.1039/d2md00330a
Chlastakova, A.; Kascakova, B.; Kotal, J.; Langhansova, H.; Kotsyfakis, M.; Kuta Smatanova, I.; Tirloni, L.; Chmelar, J.: Iripin-1, a new anti-inflammatory tick serpin, inhibits leukocyte recruitment in vivo while altering the levels of chemokines and adhesion molecules. , Frontiers in Immunology 14 (2023), p. 1116324/1-16
doi: 10.3389/fimmu.2023.1116324
Barwiolek, M.; Jankowska, D.; Kaczmarek-Kedziera, A.; Lakomska, I.; Kobylarczyk, J.; Podgajny, R.; Popielarski, P.; Masternak, J.; Witwicki, M.; Muziol, T.M.: New Dinuclear Macrocyclic Copper(II) Complexes as Potentially Fluorescent and Magnetic Materials. , International Journal of Molecular Sciences 24 (2023), p. 3017/1-24
doi: 10.3390/ijms24033017
Tröster, A.; DiPrima, M.; Jores, N.; Kudlinzki, D.; Sreeramulu, S.; Grande, S.L.; Linhard, V.; Ludig, D.; Schug, A.; Saxena, K.; Reinecke, M.; Heinzlmeir, S.; Leisegang, M.S.; Wollenhaupt, J.; Lennartz, F.; Weiss, M.S.; Kuster, B.; Tosato, G.; Schwalbe, H.: Optimization of the Lead Compound NVP-BHG712 as Colorectal Cancer Inhibitor. , Chemistry - A European Journal 29 (2023), p. e202203967/1-11
doi: 10.1002/chem.202203967
Löffler, Jan Gerrit: Protein vibrational energy transfer: new sensors and application in an enzyme active site. , Uni Frankfurt, 2023
Michel, F.; Romero-Romero, S.; Höcker, B.: Retracing the evolution of a modern periplasmic binding protein. , Protein Science 32 (2023), p. e4793/1-13
doi: 10.1002/pro.4793
Sun, S.; Fushimi, M.; Rossetti, T.; Kaur, N.; Ferreira, J.; Miller, M.; Quast, J.; van den Heuvel, J.; Steegborn, C.; Levin, L.R.; Buck, J.; Myers, R.W.; Kargman, S.; Liverton, N.; Meinke, P.T.; Huggins, D.J.: Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation. , Journal of Chemical Information and Modeling 63 (2023), p. 2828-2841
doi: 10.1021/acs.jcim.2c01577
Schmidt, A.; Kalms, J.; Lorent, C.; Katz, S.; Frielingsdorf, S.; Evans, R.M.; Fritsch, J.; Siebert, E.; Teutloff, C.; Armstrong, F.A.; Zebger, I.; Lenz, O.; Scheerer, P.: Stepwise conversion of the Cys6[4Fe-3S] to a Cys4[4Fe-4S] cluster and its impact on the oxygen tolerance of [NiFe]-hydrogenase. , Chemical Science 14 (2023), p. 11105-11120
doi: 10.1039/d3sc03739h
Pasch, T.; Schröder, A.; Kattelmann, S.; Eisenstein, M.; Pietrokovski, S.; Kümmel, D.; Mootz, H.D.: Structural and biochemical analysis of a novel atypically split intein reveals a conserved histidine specific to cysteine-less inteins. , Chemical Science 14 (2023), p. 5204-5213
doi: 10.1039/d3sc01200j
Job, L.; Kohler, A.; Eichinger, A.; Testanera, M.; Escher, B.; Worek, F.; Skerra, A.: Structural and Functional Analysis of a Highly Active Designed Phosphotriesterase for the Detoxification of Organophosphate Nerve Agents Reveals an Unpredicted Conformation of the Active Site Loop. , Biochemistry 62 (2023), p. 942-955
doi: 10.1021/acs.biochem.2c00666
Talaj, J.A.; Zielinski, K.; Bujacz, A.: Structural Investigation of Diclofenac Binding to Ovine, Caprine, and Leporine Serum Albumins. , International Journal of Molecular Sciences 24 (2023), p. 1534/1-14
doi: 10.3390/ijms24021534
Haldar, S.; Bhauriyal, P.; Ramuglia, A.R.; Khan, A.H.; De Kock, S.; Hazra, A.; Bon, V.; Pastoetter, D.L.; Kirchhoff, S.; Shupletsov, L.; De, A.; Isaacs, M.A.; Feng, X.; Walter, M.; Brunner, E.; Weidinger, I.M.; Heine, T.; Schneemann, A.; Kaskel, S.: Sulfide-Bridged Covalent Quinoxaline Frameworks for Lithium-Organosulfide Batteries. , Advanced Materials 35 (2023), p. 2210151/1-14
doi: 10.1002/adma.202210151
Kunert, S.; Linhard, V.; Weirich, S.; Choudalakis, M.; Osswald, F.; Krämer, L.; Köhler, A.R.; Bröhm, A.; Wollenhaupt, J.; Schwalbe, H; Jeltsch, A: The MECP2-TRD domain interacts with the DNMT3A-ADD domain at the H3-tail binding site. , Protein Science 32 (2023), p. e4542/1-14
doi: 10.1002/pro.4542
Maity, K.; Bon, V.; Kaskel, S.: Toward Controlled Partial Desolvation of Guest-Responsive Metal-Organic Frameworks for Precise Porosity Control. , Chemistry of Materials 35 (2023), p. 4192-4200
doi: 10.1021/acs.chemmater.3c00069
Hao, Y.; Velkos, G.; Schiemenz, S.; Rosenkranz, M.; Wang, Y.; Büchner, B.; Avdoshenko, S.M.; Popov, A.A.; Liu, F.: Using internal strain and mass to modulate Dy⋯Dy coupling and relaxation of magnetization in heterobimetallic metallofullerenes DyM2N@C80 and Dy2MN@C80 (M = Sc, Y, La, Lu). , Inorganic Chemistry Frontiers 10 (2023), p. 468-484
doi: 10.1039/d2qi02224a
2022
Kordes, S.; Romero-Romero, S.; Lutz, L.; Höcker, B.: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. , Protein Science 31 (2022), p. 513-527
doi: 10.1002/pro.4249
Marjault, H.B.; Karmi, O.; Zuo, K.; Michaeli, D.; Eisenberg-Domovich, Y.; Rossetti, G.; de Chassey, B.; Vonderscher, J.; Cabantchik, I.; Carloni, P.; Mittler, R.; Livnah, O.; Meldrum, E.; Nechushtai, R.: An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters. , Communications Biology 5 (2022), p. 437/1-9
doi: 10.1038/s42003-022-03393-x
Wu, F.; Ma, J.; Lombardi, F.; Fu, Y.; Liu, F; Huang, Z.; Liu, R.; Komber, H.; Alexandropoulos, D.I.; Dmitrieva, E.; Lohr, T.G.; Israel, N.; Popov, A.A.; Liu, J.; Bogani, L.; Feng, X.: Benzo-Extended Cyclohepta[def]fluorene Derivatives with Very Low-Lying Triplet States. , Angewandte Chemie - International Edition 61 (2022), p. e202202170/1-7
doi: 10.1002/anie.202202170
Tsika, A.C.; Gallo, A.; Fourkiotis, N.K.; Argyriou, A.I.; Sreeramulu, S.; Löhr, F.; Rogov, V.V.; Richter, C.; Linard, V.; Gande, S.L.; Altincekic, N.; Krishnatas, R.; Elamri, I.; Schwalbe, H.; Wollenhaupt, J.; Weiss, M.S.; Spyroulias, G.A.: Binding adaptation of GS-441524 diversifies macro domains and downregulate SARS-CoV-2 de-MARylation capacity. , Journal of Molecular Biology : jmb 434 (2022), p. 16772/1-21
doi: 10.1016/j.jmb.2022.167720
Malecki, P.H.; Imiolczyk, B.; Barciszewski, J.; Czyrko-Horczak, J.; Sliwiak, J.; Gawel, M.; Wozniak, K.; Jaskolski, M.; Brzezinski, K.: Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803. , Acta Crystallographica Section D - Structural biology 78 (2022), p. 865-882
doi: 10.1107/S2059798322005605
Data-doi: 10.18150/JWPKAB
Data-doi: 10.18150/1KE3PW
Data-doi: 10.18150/IRFZHN
Braun, N.J.; Huber, S.; Schmacke, L.C.; Heine, A.; Steinmetzer, T.: Boroleucine-Derived Covalent Inhibitors of the ZIKV Protease. , ChemMedChem 18 (2022), p. e202200336/1-8
doi: 10.1002/cmdc.202200336
Yang, W.; Velkos, G.; Sudarkova, S.; Büchner, B.; Avdoshenko, S.M.; Liu, F.; Popov, A.A.; Chen, N.: Carbon cage isomers and magnetic Dy⋯Dy interactions in Dy2O@C88 and Dy2C2@C88 metallofullerenes. , Inorganic Chemistry Frontiers 9 (2022), p. 5805-5819
doi: 10.1039/d2qi01796b
Cociurovscaia, A.; Bujacz, G.; Pietrzyk-Brzezinska, A.J.: Crystal structure of the Escherichia coli CusS kinase core. , Journal of Structural Biology 214 (2022), p. 107883/1-7
doi: 10.1016/j.jsb.2022.107883
Kasmaei, K.M.; Kalyani, D.C.; Reichenbach, T.; Jimenez-Quero, A.; Vilaplana, F.; Divne, C.: Crystal structure of the feruloyl esterase from Lentilactobacillus buchneri reveals a novel homodimeric state. , Frontiers in Microbiology 13 (2022), p. 1050160/1-13
doi: 10.3389/fmicb.2022.1050160
Sonani, R.R.; Blat, A.; Dubin, G.: Crystal structures of apo- and FAD-bound human peroxisomal acyl-CoA oxidase provide mechanistic basis explaining clinical observations. , International Journal of Biological Macromolecules 205 (2022), p. 203-210
doi: 10.1016/j.ijbiomac.2022.02.008
Rhys, G.G.; Cross, J.A.; Dawson, W.M.; Thompson, H.F.; Shanmugaratnam, S.; Savery, N.J.; Dodding, M.P.; Höcker, B.; Woolfson, D.N.: De novo designed peptides for cellular delivery and subcellular localisation. , Nature Chemical Biology 18 (2022), p. 999–1004
doi: 10.1038/s41589-022-01076-6
Data-doi: 10.5281/zenodo.6519961
Giammarinaro, P.I.; Young, M.K.M.; Steinchen, W.; Mais, C.N.; Hochberg, G.; Yang, J.; Stevenson, D.M.; Amador-Noguez, D.; Paulus, A.; Wang, J.D.; Bange, G.: Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. , Nature Microbiology 7 (2022), p. 1442-1452
doi: 10.1038/s41564-022-01193-x
Dahms, S.O.; Schnapp, G.; Winter, M.; Buttner, F.H.; Schleputz, M.; Gnamm, C.; Pautsch, A.; Brandstetter, H.: Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism. , ACS Chemical Biology 17 (2022), p. 816-821
doi: 10.1021/acschembio.2c00103
Gilzer, D.; Schreiner, M.; Niemann, H.H.: Direct interaction of a chaperone-bound type III secretion substrate with the export gate. , Nature Communications 13 (2022), p. 2858/1-13
doi: 10.1038/s41467-022-30487-1
Gao, S.; Song, L.; Claff, T.; Woodson, M.; Sylvester, K.; Jing, L.; Weisse, R.H.; Cheng, Y.; Straeter, N.; Schaekel, L.; Guetschow, M.; Ye, B.; Yang, M.; Zhang, T.; Kang, D.; Toth, K.; Tavis, J.; Tollefson, A.E.; Mueller, C.E.; Zhan, P.; Liu, X.: Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors. , Journal of Medicinal Chemistry 65 (2022), p. 16902-16917
doi: 10.1021/acs.jmedchem.2c01716
Gao, S.; Sylvester, K.; Song, L.; Claff, T.; Jing, L.; Woodson, M.; Weisse, R. H.; Cheng, Y.; Schaekel, L.; Petry, M.; Guetschow, M.; Schiedel, A.C.; Straeter, N.; Kang, D.; Xu, S.; Toth, K.; Tavis, J.; Tollefson, A.E.; Mueller, C.E.; Liu, X.; Zhan, P.: Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity. , Journal of Medicinal Chemistry 65 (2022), p. 13343-13364
doi: 10.1021/acs.jmedchem.2c01146
Dolot, R.; Maciaszek, A.; Mikolajczyk, B.; Nawrot, B.: First High-Resolution Crystal Structures of DNA:2'-O-Methyl-RNA Heteroduplexes. , Crystals (Basel) 12 (2022), p. 760/1-16
doi: 10.3390/cryst12060760
Leppkes, J.; Dimos, N.; Loll, B.; Hohmann, T.; Dyrks, M.; Wieseke, A.; Keller, B.G.; Koksch, B.: Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin. , RSC Chemical Biology 3 (2022), p. 773-782
doi: 10.1039/d2cb00018k
Fietze, T.; Wilk, P.; Kabinger, F.; Anoosheh, S.; Hofer, A.; Lundin, D.; Feiler, C.G.; Weiss, M.S.; Loderer, C.: HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase. , Biochemistry 61 (2022), p. 1633-1641
doi: 10.1021/acs.biochem.2c00173
Manikandan, P.; Sandhya, S.; Nadig, K.; Paul, S.; Srinivasan, N.; Rothweiler, U.; Singh, M.: Identification, functional characterization, assembly and structure of ToxIN type III toxin-antitoxin complex from E. coli. , Nucleic Acids Research 50 (2022), p. 1687-1700
doi: 10.1093/nar/gkab1264
Weigert, S.; Perez-Garcia, P.; Gisdon, F.J.; Gagsteiger, A.; Schweinshaut, K.; Ullmann, G.M.; Chow, J.; Streit, W.R.; Höcker, B.: Investigation of the halophilic PET hydrolase PET6 from Vibrio gazogenes. , Protein Science 31 (2022), p. e4500/1-16
doi: 10.1002/pro.4500
Zhang, J.-J.; Ma, J.; Liu, F.; Cui, L.-S.; Fu, Y.; Yang, L.; Popov, A.A.; Weigand, J.J.; Liu, J.; Feng, X.: Large Acene Derivatives with B–N Lewis Pair Doping: Synthesis, Characterization, and Application. , Organic Letters 24 (2022), p. 1877-1882
doi: 10.1021/acs.orglett.2c00033
Huskova, A.; Dinesh, D.C.; Srb, P.; Boura, E.; Veverka, V.; Silhan, J.: Model of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model. , Nucleic Acids Research 50 (2022), p. 10436–10448
doi: 10.1093/nar/gkac793
Dang, T.; Loll, B.; Müller, S.; Skobalj, R.; Ebeling, J.; Bulatov, T.; Gensel, S.; Göbel, J.; Wahl, M.C.; Genersch, E.; Mainz, A.; Süssmuth, R.D.: Molecular basis of antibiotic self-resistance in a bee larvae pathogen. , Nature Communications 13 (2022), p. 2349/1-11
doi: 10.1038/s41467-022-29829-w
Lindenblatt, D.; Applegate, V.; Nickelsen, A.; Klußmann, M.; Neundorf, I.; Götz, C.; Jose, J.; Niefind, K.: Molecular Plasticity of Crystalline CK2alpha' Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity. , Journal of Medicinal Chemistry 65 (2022), p. 1302–1312
doi: 10.1021/acs.jmedchem.1c00063
Loch, J.I.; Barciszewski, J.; Sliwiak, J.; Bonarek, P.; Wrobel, P.; Pokrywka, K.; Shabalin, I.G.; Minor, W.; Jaskolski, M.; Lewinski, K.: New ligand-binding sites identified in the crystal structures of beta-lactoglobulin complexes with desipramine. , IUCrJ 9 (2022), p. 386-398
doi: 10.1107/S2052252522004183
Graf, L.; Liu, F.; Naumann, M.; Büchner, B.; Krupskaya, Y.; Popov, A.A.; Knupfer, M.: Optical Anisotropy and Momentum-Dependent Excitons in Dibenzopentacene Single Crystals. , ACS Omega 7 (2022), p. 21183-21191
doi: 10.1021/acsomega.2c01987
Haldar, S.; Wang, M.; Bhauriyal, P.; Hazra, A.; Khan, A.H.; Bon, V.; Isaacs, M.A.; De, A.; Shupletsov, L.; Boenke, T.; Grothe, J.; Heine, T.; Brunner, E.; Feng, X.; Dong, R.; Schneemann, A.; Kaskel, S.: Porous Dithiine-Linked Covalent Organic Framework as a Dynamic Platform for Covalent Polysulfide Anchoring in Lithium-Sulfur Battery Cathodes. , Journal of the American Chemical Society 144 (2022), p. 9101-9112
doi: 10.1021/jacs.2c02346
Dietler, J.; Gelfert, R.; Kaiser, J.; Borin, V.; Renzl, C.; Pilsl, S.; Ranzani, A.T.; Garcia de Fuentes, A.; Gleichmann, T.; Diensthuber, R.P.; Weyand, M.; Mayer, G.; Schapiro, I.; Möglich, A.: Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine. , Nature Communications 13 (2022), p. 2618/1-16
doi: 10.1038/s41467-022-30252-4
Data-doi: 10.5281/zenodo.6341885
Burmeister, D.; Müller, J.; Plaickner, J.; Kochovski, Z.; List-Kratochvil, E.J.W.; Bojdys, M.: Size Effects of the Anions in the Ionothermal Synthesis of Carbon Nitride Materials. , Chemistry - A European Journal 28 (2022), p. e202200705/1-8
doi: 10.1002/chem.202200705
Muziol, T.M.; Tereba, N.; Podgajny, R.; Pelka, R.; Czernia, D.; Wisniewski, M.; Koter, S.; Wrzeszcz, G.: Sorption and Magnetic Properties of Oxalato-Based Trimetallic Open Framework Stabilized by Charge-Assisted Hydrogen Bonds. , International Journal of Molecular Sciences 23 (2022), p. 1556/1-22
doi: 10.3390/ijms23031556
Nagel, F.; Palm, G.J.; Geist, N.; McDonnell, T.C.R.; Susemihl, A.; Girbardt, B.; Mayerle, J.; Lerch, M.M.; Lammers, M.; Delcea, M.: Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin. , International Journal of Molecular Sciences 23 (2022), p. 3468/1-14
doi: 10.3390/ijms23073468
Barwiolek, M.; Jankowska, D.; Kaczmarek-Kedziera, A.; Muziol, T.M.: Structural and optical properties of the p-alkylated 2,6-bis(benzimidazol)phenoles obtained from o-phenylenediamine and their sensitive behavior towards zinc(II) ions. , Polyhedron 224 (2022), p. 116004/1-15
doi: 10.1016/j.poly.2022.116004
Wang, Jianhui: Structural Basis of Gene Regulation by the Transcription Factors Tfcp2l1 and Tfcp2. , FU Berlin, 2022
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Stieler, Martin: Structure-Based Design of a Blood Coagulation Factor XIII Blocker. , Uni Marburg, 2017
Barone, Matthias: Structure-optimized ProM scaffolds address Ena/VASP as a possible antimetastatic target. , Berlin, Freie Universität Berlin, Diss., 2017
Barciszewski, Jakub: Strukturalne podstawy działania ludzkiej mięśniowej fosfatazy fruktozo-1,6-bisfosforanu = Structural basis of fructose-1,6-bisphosphatase function. , Poznan, Institute of Bioorganic Chemistry, Polish Academy of Sciences, thesis, 2017
Wilk, P.; Uehlein, M.; Kalms, J.; Dobbek, H.; Mueller, U.; Weiss, M.S.: Substrate specificity and reaction mechanism of human prolidase. , FEBS Journal 284 (2017), p. 2870-2885
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Kutzscher, Christel; Janssen-Müller, Daniel; Notzon, Andreas; Stoeck, Ulrich; Bon, Volodymyr; Senkovska, Irena; Kaskel, Stefan; Glorius, Frank: Synthesis of the homochiral metal-organic framework DUT-129 based on a chiral dicarboxylate linker with 6 stereocenters. , CrystEngComm 19 (2017), p. 2494-2499
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Krimmer, Stefan Günter: Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study. , Uni Marburg, 2017
Kalms, J.; Banthiya, S.; Galemou Yoga, E.; Hamberg, M.; Holzhutter, H.-G.; Kuhn, H.; Scheerer, P.: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. , Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1862 (2017), p. 463-473
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Eichinger, A.; Neumaier, I.; Pschenitza, M.; Niessner, R.; Knopp, D.; Skerra, A.: Tight Molecular Recognition of Benzo[a] pyrene by a High-Affinity Antibody. , Angewandte Chemie - International Edition 56 (2017), p. 10592-10597
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Radeva, N.; Schiebel, J.; Wang, X.; Krimmer, S.G.; Fu, K.; Stieler, M.; Ehrmann, F.R.; Metz, A.; Rickmeyer, T.; Betz, M.; Winquist, J.; Park, A.Y.; Huschmann, F.U.; Weiss, M.S.; Mueller, U.; Heine, A.; Klebe, G.: Active Site Mapping of an Aspartic Protease by Multiple Fragment Crystal Structures: Versatile Warheads To Address a Catalytic Dyad. , Journal of Medicinal Chemistry 59 (2016), p. 9743-9759
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Antonios, Gregory: Amyloid beta 4-42 in Alzheimer’s disease: Target, Therapy, Mechanism. , Uni Göttingen, 2016
Gilski, M.; Drozdzal, P.; Kierzek, R.; Jaskolski, M.: Atomic resolution structure of a chimeric DNA-RNA Z-type duplex in complex with Ba(2+) ions: a case of complicated multi-domain twinning. , Acta Crystallographica Section D - Structural biology 72 (2016), p. 211-223
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Rühmann, E.H.; Rupp, M.; Betz, M.; Heine, A.; Klebe, G.: Boosting Affinity by Correct Ligand Preorganization for the S2 Pocket of Thrombin: A Study by Isothermal Titration Calorimetry, Molecular Dynamics, and High-Resolution Crystal Structures. , ChemMedChem 11 (2016), p. 309-319
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Maiwald, A.; Hammami, M.; Wagner, S.; Heine, A.; Klebe, G.; Steinmetzer, T.: Changing the selectivity profile - from substrate analog inhibitors of thrombin and factor Xa to potent matriptase inhibitors. , Journal of Enzyme Inhibition and Medicinal Chemistry 31 (2016), p. 89-97
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Schulte, T.; Liu, L.; Panas, M.D.; Thaa, B.; Dickson, N.; Gotte, B.; Achour, A.; McInerney, G.M.: Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication. , Open Biology 6 (2016), p. 160078/1-15
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Navratil, M.; Tykvart, J.; Schimer, J.; Pachl, P.; Navratil, V.; Rokob, T.A.; Hlouchova, K.; Rulisek, L.; Konvalinka, J.: Comparison of human glutamate carboxypeptidases II and III reveals their divergent substrate specificities. , FEBS Journal 283 (2016), p. 2528-2545
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Yoga-Galemou, Etienne: Crystal structure analysis of the bacterial lipoxygenase from Pseudomonas aeruginosa. , Berlin, Freie Universität Berlin, Master, 2016
Mills, S.J.; Silvander, C.; Cozier, G.; Tresaugues, L.; Nordlund, P.; Potter, B.V.: Crystal Structures of Type-II Inositol Polyphosphate 5-Phosphatase INPP5B with Synthetic Inositol Polyphosphate Surrogates Reveal New Mechanistic Insights for the Inositol 5-Phosphatase Family. , Biochemistry 55 (2016), p. 1384-1397
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Dolot, R.; Kaczmarek, R.; Seda, A.; Krakowiak, A.; Baraniak, J.; Nawrot, B.: Crystallographic studies of the complex of human HINT1 protein with a non-hydrolyzable analog of Ap4A. , International Journal of Biological Macromolecules 87 (2016), p. 62-69
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Zender, M.; Witzgall, F.; Drees, S.L.; Weidel, E.; Maurer, C.K.; Fetzner, S.; Blankenfeldt, W.; Empting, M.; Hartmann, R.W.: Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds. , ACS Chemical Biology 11 (2016), p. 1755-1763
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Graczer, E.; Szimler, T.; Garamszegi, A.; Konarev, P.V.; Labas, A.; Olah, J.; Pallo, A.; Svergun, D.I.; Merli, A.; Zavodszky, P.; Weiss, M.S.; Vast, M.: Dual Role of the Active Site Residues of Thermus thermophilus 3-Isopropylmalate Dehydrogenase: Chemical Catalysis and Domain Closure. , Biochemistry 55 (2016), p. 560-574
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Baranovic, J.; Chebli, M.; Salazar, H.; Carbone, A.L.; Faelber, K.; Lau, A.J.; Daumke, O.; Plested, A.J.R.: Dynamics of the ligand binding domain layer during AMPA receptor activation. , Biophysical Journal 110 (2016), p. 896-911
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Radeva, Nedyalka: From Active-Site Mapping to Lead Discovery using Fragment-based Approaches on the Aspartic protease Endothiapepsin. , Uni Marburg, 2016
Le Cong, Karoline-Luisa: Herstellung, Kristallisation und Strukturaufklärung von bovinem Rhodopsin im Komplex mit verschiedenen von G-Proteinen abgeleiteten Peptiden. , Berlin, Freie Universität Berlin, Bachelor, 2016
Rauth, S.; Hinz, D.; Borger, M.; Uhrig, M.; Mayhaus, M.; Riemenschneider, M.; Skerra, A.: High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide. , Biochemical Journal 473 (2016), p. 1563-1578
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Schiebel, J.; Krimmer, S.G.; Röwer, K.; Knörlein, A.; Wang, X.; Park, A.Y.; Stieler, M.; Ehrmann, F.R.; Fu, K.; Radeva, N.; Krug, M.; Huschmann, F.U.; Glöckner, S.; Weiss, M.S.; Mueller, U.; Klebe, G.; Heine, A.: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. , Structure 24 (2016), p. 1398-1409
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Siva, M.; Svoboda, M.; Veverka, V.; Trempe, J.-F.; Hofmann, K.; Kozisek, M.; Hexnerova, R.; Sedlak, F.; Belza, J.; Brynda, J.; Sacha, P.; Hubalek, M.; Starkova, J.; Flaisigova, I.; Konvalinka, J.; Saskova, K.G.: Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog. , Scientific Reports 6 (2016), p. 30443/1-15
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Werten, S.; Schneider, J.; Palm, G.J.; Hinrichs, W.: Modular organisation of inducer recognition and allostery in the tetracycline repressor. , FEBS Journal 283 (2016), p. 2102-2114
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Doležal, M.; Zabransky, A.; Dostal, J.; Vanek, O.; Brynda, J.; Lepsík, M.; Hadravová, R.; Pichová, I.: Myristoylation drives dimerization of matrix protein from mouse mammary tumor virus. , Retrovirology 13 (2016), p. 1-15
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Neeb, M.; Hohn, C.; Ehrmann, F.R.; Härtsch, A.; Heine, A.; Diederich, F.; Klebe, G.: Occupying a flat subpocket in a tRNA-modifying enzyme with ordered or disordered side chains: Favorable or unfavorable for binding? , Bioorganic & Medicinal Chemistry 24 (2016), p. 4900-4910
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Hnizda, A.; Skerlova, J.; Fabry, M.; Pachl, P.; Sinalova, M.; Vrzal, L.; Man, P.; Novak, P.; Rezacova, P.; Veverka, V.: Oligomeric interface modulation causes misregulation of purine 5 '-nucleotidase in relapsed leukemia. , BMC Biology 14 (2016), p. 91
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Braun, B.M.; Traenkle, B.; Koch, A.P.; Emele, F.; Weiss, F.; Poetz, O.; Stehle, T.; Rothbauer, U.: Peptides in headlock – a novel high-affinity and versatile peptidebinding nanobody for proteomics and microscopy. , Scientific Reports 6 (2016), p. 19211/1-10
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Zhang, Linlin: Proteases of Emerging Viruses as Targets for Broad-Spectrum Inhibitors. , Lübeck, Universität zu Lübeck, Diss., 2016
Mejdrova, I.; Chalupska, D.; Plackova, P.; Mueller, C.; Sala, M.; Klima, M.; Baumlova, A.; Hrebabecky, H.; Prochazkova, E.; Dejmek, M.; Strunin, D.; Weber, J.; Lee, G.; Matousova, M.; Mertlikova-Kaiserova, H.; Ziebuhr, J.; Birkus, G.; Boura, E.; Nencka, R.: Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase III beta (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology. , Journal of Medicinal Chemistry 60 (2016), p. 100-118
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Spanopoulos, I.; Tsangarakis, C.; Klontzas, E.; Tylianakis, E.; Froudakis, G.; Adil, K.; Belmabkhout, Y.; Eddaoudi, M.; Pantelis, N.T.: Reticular Synthesis of HKUST-like tbo-MOFs with Enhanced CH4 Storage. , Journal of the American Chemical Society 138 (2016), p. 1568–1574
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Lund, B.A.; Christopeit, T.; Guttormsen, Y.; Bayer, A.; Leiros, H.-K.S.: Screening and Design of Inhibitor Scaffolds for the Antibiotic Resistance Oxacillinase-48 (OXA-48) through Surface Plasmon Resonance Screening. , Journal of Medicinal Chemistry 59 (2016), p. 5542-5554
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Banthiya, S.; Kalms, J.; Yoga Galemou, E.; Ivanov, I.; Carpena, X.; Hamberg, M.; Kuhn, H.; Scheerer, P.: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. , Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1861 (2016), p. 1681-1692
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Lei, J.; Hilgenfeld, R.: Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin. , Virologica Sinica 31 (2016), p. 288-299
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Schiefner, A.; Angelov, A.; Liebl, W.; Skerra, A.: Structural basis for cellulose binding by the type A carbohydrate-binding module 64 of Spirochaeta thermophila. , Proteins - Structure, Function and Bioinformatics 84 (2016), p. 855-858
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Thorsell, A.G.; Ekblad, T.; Karlberg, T.; Löw, M.; Pinto, A.F.; Tresaugues, L.; Moche, M.; Cohen, M.S.; Schüler, H.: Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors. , Journal of Medicinal Chemistry 60 (2016), p. 1262-1271
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Sekula, B.; Ciesielska, A.; Rytczak, P.; Koziolkiewicz, M.; Bujacz, A.: Structural evidence of the species-dependent albumin binding of the modified cyclic phosphatidic acid with cytotoxic properties. , Bioscience Reports 36 (2016), p. e00338
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Sekula, B.; Bujacz, A.: Structural Insights into the Competitive Binding of Diclofenac and Naproxen by Equine Serum Albumin. , Journal of Medicinal Chemistry 59 (2016), p. 82-89
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Dannoon, S.; Ganguly, T.; Cahaya, H.; Geruntho, J.J.; Galliher, M.S.; Beyer, S.K.; Choy, C.J.; Hopkins, M.R.; Regan, M.; Blecha, J.E.; Skultetyova, L.; Drake, C.R.; Jivan, S.; Barinka, C.; Jones, E.F.; Berkman, C.E.; VanBrocklin, H.F.: Structure-Activity Relationship of F-18-Labeled Phosphoramidate Peptidomimetic Prostate-Specific Membrane Antigen (PSMA)-Targeted Inhibitor Analogues for PET Imaging of Prostate Cancer. , Journal of Medicinal Chemistry 59 (2016), p. 5684-5694
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Kundu, P.; Biswas, R.; Mukherjee, S.; Reinhard, L.; Dutta, A.; Mueller-Dieckmann, J.; Weiss, M.S.; Pal, N.K.; Das, A.K.: Structure-based Epitope Mapping of Mycobacterium tuberculosis Secretary Antigen MTC28. , Journal of Biological Chemistry 291 (2016), p. 13943-13954
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Ehrmann, Frederik Rainer: Strukturbasierte Entwicklung und Charakterisierung von Inhibitoren der TGT,ein mögliches Ziel zur Therapie der Bakterienruhr. , Uni Marburg, 2016
Horsten, Silke von: Strukturelle Basis signalinduzierter Änderungen in Phytochrom B sowie der Phytochrom-assoziierten Proteinphosphatase PAPP5. , Uni Marburg, 2016
Nagano, S.; Scheerer, P.; Zubow, K.; Michael, N.; Inomata, K.; Lamparter, T.; Krauss, N.: The Crystal Structures of the N-terminal Photosensory Core Module of Agrobacterium Phytochrome Agp1 as Parallel and Anti-parallel Dimers. , Journal of Biological Chemistry 291 (2016), p. 20674-20691
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Kiliszek, A.; Katarzyna Banaszak, K.; Dauter, Z.; Rypniewski, W.: The first crystal structures of RNA–PNA duplexes and a PNA-PNA duplex containing mismatches––toward anti-sense therapy against TREDs. , Nucleic Acids Research 44 (2016), p. 1937-1943
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Kiliszek, A.; Katarzyna Banaszak, K.; Dauter, Z.; Rypniewski, W.: The first crystal structures of RNA–PNA duplexes and a PNA-PNA duplex containing mismatches––toward anti-sense therapy against TREDs. , Nucleic Acids Research 44 (2016), p. 1937-1943
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Gerlach, M.; Müller, U.; Weiss, M.S.: The MX Beamlines BL14.1-3 at BESSY II. , Journal of Large Scale Research Facilities JLSRF 2 (2016), p. 2-47
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Müller, P.; Grünker, R.; Bon, V.; Pfeffermann, M.; Senkovska, I.; Weiss, M.S.; Feng, X.; Kaskel, S.: Topological control of 3,4-connected frameworks based on the Cu2-paddle-wheel node: tbo or pto, and why? , CrystEngComm 18 (2016), p. 8164-8171
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Barciszewski, J.; Wisniewski, J.; Kolodziejczyk, R.; Jaskolski, M.; Rakus, D.; Dzugaj, A.: T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure. , Acta Crystallographica Section D - Structural biology 72 (2016), p. 536-550
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Bon, V.; Kavoosi, N.; Senkovska, I.; Müller, P.; Schaber, J.; Wallacher, D.; Többens, D.M.; Mueller, U.; Kaskel, S.: Tuning the flexibility in MOFs by SBU functionalization. , Dalton Transactions 45 (2016), p. 4407-4415
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Drozdzal, P.; Gilski, M.; Jaskolski, M.: Ultrahigh-resolution centrosymmetric crystal structure of Z-DNA reveals the massive presence of alternate conformations. , Acta Crystallographica Section D - Structural biology 72 (2016), p. 1203-1211
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Novakova, Z.; Wozniak, K.; Jancarik, A.; Rais, R.; Wu, Y.; Pavlicek, J.; Ferraris, D.; Havlinova, B.; Ptacek, J.; Vavra, J.; Hin, N.; Rojas, C.; Majer, P.; Slusher, B.S.; Tsukamoto, T.; Barinka, C.: Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity. , Journal of Medicinal Chemistry 59 (2016), p. 4539-4550
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Drache, F.; Bon, V.; Senkovska, I.; Adam, M.; Eychmüller, A.; Kaskel, S.: Vapochromic Luminescence of a Zirconium-Based Metal–Organic Framework for Sensing Applications. , European Journal of Inorganic Chemistry 2016 (2016), p. 4483-4489
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Rypniewski, W.; Banaszak, K.; Kulinski, T.; Kiliszek, A.: Watson-Crick-like pairs in CCUG repeats : evidence for tautomeric shifts or protonation. , RNA 22 (2016), p. 22-31
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Rypniewski, W.; Banaszak, K.; Kulinski, T.; Kiliszek, A.: Watson-Crick-like pairs in CCUG repeats : evidence for tautomeric shifts or protonation. , RNA 22 (2016), p. 22-31
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Sparta, K.; Krug, M.; Heinemann, U.; Mueller, U.; Weiss, M.S.: XDSAPP 2.0. , Journal of Applied Crystallography 49 (2016), p. 1085-1092
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Liu, S.; Mozaffari-Jovin, S.; Wollenhaupt, J.; Santos, K.F.; Theuser, M.; Dunin-Horkawicz, S.; Fabrizio, P.; Bujnicki, J.M.; Lührmann, R.; Wahl, M.C.: A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing. , eLife 4 (2015), p. e07320/1-23
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Absmeier, E.; Rosenberger, L.; Apelt, L.; Becke, C.; Santos, K.F.; Stelzl, U.; Wahl, M.C.: A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein. , Acta Crystallographica Section D - Biological Crystallography 71 (2015), p. 762-771
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Dostal, J.; Pecina, A.; Hruskova-Heidingsfeldova, O.; Mareckova, L.; Pichova, I.; Rezacova, P.; Lepsik, M.; Brynda, J.: Atomic resolution crystal structure of Sapp2p, a secreted aspartic protease from Candida parapsilosis. , Acta Crystallographica Section D - Biological Crystallography 71 (2015), p. 2494-2504
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Fesseler, Jochen Martin: Biochemische und strukturelle Untersuchungen der Kohlenmonoxid-Dehydrogenasen CODH-II und CODH-V aus Carboxydothermus hydrogenoformans. , Berlin, Humboldt Universität, Diss., 2015
Buemi, M.R.; De Luca, L.; Ferro, S.; Bruno, E.; Ceruso, M.; Supuran, C.T.; Pospisilova, K.; Brynda, J.; Rezacova, P.; Gitto, R.: Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms. , European Journal of Medicinal Chemistry 102 (2015), p. 223-232
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Youn, S.; Kim, K.I.; Ptacek, J.; Ok, K.; Novakova, Z.; Kim, Y.H.; Koo, J.H.; Barinka, C.; Byun, Y.: Carborane-containing urea-based inhibitors of glutamate carboxypeptidase II: Synthesi87382s and structural characterization. , Bioorganic & Medicinal Chemistry Letters 25 (2015), p. 5232-5236
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Schiefner, A.; Freier, R.; Eichinger, A.; Skerra, A.: Crystal structure of the human odorant binding protein, OBPIIa. , Proteins - Structure, Function and Bioinformatics 83 (2015), p. 1180-1184
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Han, Z.; Sakai, N.; Boettger, L.H.; Klinke, S.; Hauber, J.; Trautwein, A.X.; Hilgenfeld, R.: Crystal Structure of the Peroxo-diiron(III) Intermediate of Deoxyhypusine Hydroxylase, an Oxygenase Involved in Hypusination. , Structure 23 (2015), p. 882-892
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Stevens, Tammo: Crystallographic Investigations on the Photosensory Core Module of Agrobacterium tumefaciens Phytochrome 2 (Agp2). , Berlin, Freie Universität Berlin, Bachelor, 2015
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Sommer, B.; von Moeller, H.; Haack, M.; Qoura, F.; Langner, C.; Bourenkov, G.; Garbe, D.; Loll, B.; Bruck, T.: Detailed Structure-Function Correlations of Bacillus subtilis Acetolactate Synthase. , ChemBioChem 16 (2015), p. 110-118
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Skerlova, J.; Fabry, M.; Hubalek, M.; Otwinowski, Z.; Rezacova, P.: Structure of the effector-binding domain of deoxyribonucleoside regulator DeoR from Bacillus subtilis. , FEBS Journal 281 (2014), p. 4280-4292
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Mondal, M.; Radeva, N.; Koster, H.; Park, A.; Potamitis, C.; Zervou, M.; Klebe, G.; Hirsch, A.K.: Structure-based design of inhibitors of the aspartic protease endothiapepsin by exploiting dynamic combinatorial chemistry. , Angewandte Chemie - International Edition 53 (2014), p. 3259-3263
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Eggenstein, E.; Eichinger, A.; Kim, H.-J.; Skerra, A.: Structure-guided engineering of Anticalins with improved binding behavior and biochemical characteristics for application in radio-immuno imaging and/or therapy. , Journal of Structural Biology 185 (2014), p. 203-214
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Pachl, P.; Fabry, M.; Rosenberg, I.; Simak, O.; Rezacova, P.; Brynda, J.: Structures of human cytosolic and mitochondrial nucleotidases: implications for structure-based design of selective inhibitors. , Acta Crystallographica Section D - Biological Crystallography 70 (2014), p. 461-470
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Zebisch, M.; Krauss, M.; Schäfer, P.; Sträter, N.: Structures of Legionella pneumophila NTPDase1 in complex with polyoxometallates. , Acta Crystallographica Section D - Biological Crystallography 70 (2014), p. 1147-1154
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Bujacz, A.; Zielinski, K.; Sekula, B.: Strucural studies of bovine, equine, and leporine serum albumin complexes with naproxen. , Proteins - Structure, Function and Bioinformatics 82 (2014), p. 2199-2208
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Uhlmann, Stefanie: Studien zur α- und β-Hydroxylierung des Cyclodepsipeptides Skyllamycin aus Streptomyces sp. Acta 2897. , Berlin, Technische Universität, Diss., 2014
Haufschildt, K.; Schmelz, S.; Kriegler, T.M.; Neumann, A.; Streif, J.; Arai, H.; Heinz, D.W.; Layer, G.: The Crystal Structure of Siroheme Decarboxylase in Complex with Iron-Uroporphyrin III Reveals Two Essential Histidine Residues. , Journal of Molecular Biology : jmb 426 (2014), p. 3272-3286
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Baumlova, A.; Chalupska, D.; Rozycki, B.; Jovic, M.; Wisniewski, E.; Klima, M.; Dubankova, A.; Kloer, D.P.; Nencka, R.; Balla, T.; Boura, E.: The crystal structure of the phosphatidylinositol 4-kinase II alpha. , EMBO Reports 15 (2014), p. 1085-1092
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Biela, Inna: Untersuchung der Substratspezifität der tRNA-Guanin-Transglykosylase (TGT) aus Eukaryoten und Prokaryoten und Charakterisierung der eukaryotischen TGT. , Marburg, Philipps-Universität, Diss., 2014
Demo, G.; Papouskova, V.; Komarek, J.; Kaderavek, P.; Otrusinova, O.; Srb, P.; Rabatinova, A.; Krasny, L.; Zidek, L.; Sklenar, V.; Wimmerova, M.: X-ray vs. NMR structure of N-terminal domain of δ-subunit of RNA polymerase. , Journal of Structural Biology 187 (2014), p. 174-186
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2013
Barden, S.; Lange, S.; Tegtmeyer, N.; Conradi, J.; Sewald, N.; Backert, S.; Niemann, H.H.: A Helical RGD Motif Promoting Cell Adhesion: Crystal Structures of the Helicobacter Pylori Type IV Secretion System Pilus Protein CagL. , Structure 21 (2013), p. 1931-1941
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Sommer, Bettina I.: A new synthetic biology methodology for the cell-free production of industrial alcohols. , München, Technische Universität München, Diss., 2013
Hellert, J.; Weidner-Glunde, M.; Krausze, J.; Richter, U.; Adler, H.; Fedorov, R.; Pietrek, M.; Rückert, J.; Ritter, C.; Schulz, T.F.; Lührs, T.: A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins. , PLoS Pathogens 9 (2013), p. e1003640/1-19
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Bartasun, P.; Cieslinski, H.; Bujacz, A.; Wierzbicka-Wos, A.; Kur, J.: A Study on the Interaction of Rhodamine B with Methylthioadenosine Phosphorylase Protein Sourced from an Antarctic Soil Metagenomic Library. , PLoS One 8 (2013), p. e55697/1-11
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Wagner, Stephan: Analysing Novel Structures of Protein Complexes Requiring the Central Plant Immune Regulator EDS1. , Köln, Universität, Diss., 2013
Steigemann, Birthe; Schulz, Annina; Werten, Sebastiaan: Bacteriophage T5 Encodes a Homolog of the Eukaryotic Transcription Coactivator PC4 Implicated in Recombination-Dependent DNA Replication. , Journal of Molecular Biology : jmb 425 (2013), p. 4125-4133
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Brynda, J.; Mader, P.; Sicha, V.; Fabry, M.; Poncova, K.; Bakardiev, M.; Gruner, B.; Cigler, P.; Rezacova, P.: Carborane-based carbonic anhydrase inhibitors. , Angewandte Chemie - International Edition 52 (2013), p. 13760-13763
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Degtjarik, O.; Dopitova, R.; Puehringer, S.; Nejedla, E.; Kuty, M.; Weiss, M.S.; Hejatko, J.; Janda, L.; Smatanova, I.K.: Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of AHP2, a signal transmitter protein from Arabidopsis thaliana. , Acta Crystallographica Section F - Structural Biology and Crystallization Communications 69 (2013), p. 158-161
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Gebauer, M.; Schiefner, A.; Matschiner, G.; Skerra, A.: Combinatorial Design of an Anticalin Directed against the Extra-Domain B for the Specific Targeting of Oncofetal Fibronectin. , Journal of Molecular Biology : jmb 425 (2013), p. 780-802
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Nayeem, N.; Mayans, O.; Green, T.: Correlating Efficacy and Desensitization with GluK2 Ligand-Binding Domain Movements. , Open Biology 3 (2013), p. 130051/1-12
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Roth, C.; Gröning, J.A.D.; Kaschabek, S.R.; Schlömann, M.; Sträter, N.: Crystal structure and catalytic mechanism of chloromuconolactone dehalogenase ClcF from Rhodococcus opacus 1CP. , Molecular Microbiology 88 (2013), p. 254-267
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Zhang, F.; Scheerer, P.; Oberpichler, I.; Lamparter, T.; Krauss, N.: Crystal structure of a prokaryotic (6-4) photolyase with an Fe-S cluster and a 6,7-dimethyl-8-ribityllumazine antenna chromophore. , Proceedings of the National Academy of Sciences of the United States of America : PNAS 110 (2013), p. 7217-7222
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Kim, Y.J.; Hofmann, K.P.; Ernst, O.P.; Scheerer, P.; Choe, H.-W.; Sommer, M.E.: Crystal structure of pre-activated arrestin p44. , Nature 497 (2013), p. 142-146
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Demo, G.; Fliedrova, B.; Weignerova, L.; Wimmerova, M.: Crystallization and preliminary X-ray crystallographic analysis of recombinant β-mannosidase from Aspergillus niger. , Acta Crystallographica Section F - Structural Biology and Crystallization Communications 69 (2013), p. 288-291
doi: 10.1107/S1744309113002522
Pisackova, J; Prochazkova, K; Fabry, M; Rezacova, P: Crystallization of the Effector-Binding Domain of Repressor DeoR from Bacillus subtilis. , Crystal Growth & Design 13 (2013), p. 844-848
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Lerchner, A.; Jarasch, A.; Meining, W.; Schiefner, A.; Skerra, A.: Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. alcohol dehydrogenase toward NADH cosubstrate specificity. , Biotechnology and Bioengineering 110 (2013), p. 2803-2814
doi: 10.1002/bit.24956
Tratsiak, K.; Degtjarik, O.; Drienovska, I.; Chrast, L.; Rezacova, P.; Kuty, M.; Chaloupkova, R.; Damborsky, J.; Smatanova, I.K: Crystallographic analysis of new psychrophilic haloalkane dehalogenases: DpcA from Psychrobacter cryohalolentis K5 and DmxA from Marinobacter sp ELB17. , Acta Crystallographica Section F - Structural Biology and Crystallization Communications 69 (2013), p. 683-688
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Zebisch, M.; Krauss, M.; Schäfer, P.; Lauble, P.; Sträter, N.: Crystallographic Snapshots along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases. , Structure 21 (2013), p. 1460-1475
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Sekula, B.; Zielinski, K.; Bujacz, A.: Crystallographic studies of the complexes of bovine and equine serum albumin with 3,5-diiodosalicylic acid. , International Journal of Biological Macromolecules 60 (2013), p. 316 - 324
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Hammamy, M.Z.; Haase, C.; Hammami, M.; Hilgenfeld, R.; Steinmetzer, T.: Development and Characterization of New Peptidomimetic Inhibitors of the West Nile Virus NS2B-NS3 Protease. , ChemMedChem 8 (2013), p. 231-241
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Biela, A.; Nasief, N.N.; Betz, M.; Heine, A.; Hangauer, D.; Klebe, G.: Dissecting the hydrophobic effect on the molecular level: the role of water, enthalpy, and entropy in ligand binding to thermolysin. , Angewandte Chemie - International Edition 52 (2013), p. 1822 - 1828
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Qureshi, B.M.; Hofmann, N.E.; Arroyo-Olarte, R.D.; Nickl, B.; Hoehne, W.; Jungblut, P.R.; Lucius, R.; Scheerer, P.; Gupta, N.: Dynein light chain 8a of Toxoplasma gondii, a unique conoid-localized β-strand-swapped homodimer, is required for an efficient parasite growth. , The FASEB Journal 27 (2013), p. 1034-1047
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Koudelakova, T.; Chaloupkova, R.; Brezovsky, J.; Prokop, Z.; Sebestova, E.; Hesseler, M.; Khabiri, M.; Plevaka, M.; Kulik, D.; Kuta Smatanova, I.; Rezacova, P.; Ettrich, R.; Bornscheuer, U.T.; Damborsky, J.: Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel. , Angewandte Chemie - International Edition 52 (2013), p. 1959 - 1963
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Plazuk, D.; Zakrzewski, J.; Salmain, M.; Blauz, A.; Rychlik, B.; Strzelczyk, P.; Bujacz, A.; Bujacz, G.: Ferrocene-Biotin Conjugates Targeting Cancer Cells: Synthesis, Interaction with Avidin, Cytotoxic Properties and the Crystal Structure of the Complex of Avidin with a Biotin-Linker-Ferrocene Conjugate. , Organometallics 32 (2013), p. 5774-5783
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Kettner, K.; Kuettner, E.B.; Otto, A.; Lilie, H.; Golbik, R.P.; Sträter, N.; Kriegel, T.M.: In vivo phosphorylation and in vitro autophosphorylation-inactivation of Kluyveromyces lactis hexokinase KlHxk1. , Biochemical and Biophysical Research Communications 435 (2013), p. 313-318
doi: 10.1016/j.bbrc.2013.03.121
Chang, Kai-Chin: Investigation of higher fullerenes : trifluoromethylated derivatives of C84 cage isomers. , Berlin, Humboldt Universität, Diss., 2013
Biela, I.; Tidten-Luksch, N.; Immekus, F.; Glinca, S.; Nguyen, T.X.P.; Gerber, H.-D.; Heine, A.; Klebe, G.; Reuter, K.: Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor. , PLoS One 8 (2013), p. e64240/1-19
doi: 10.1371/journal.pone.0064240
Dahms, S.O.; Kuester, M.; Streb, C.; Roth, C.; Sträter, N.; Than, M.E.: Localization and orientation of heavy-atom cluster compounds in protein crystals using molecular replacement. , Acta Crystallographica Section D - Biological Crystallography 69 (2013), p. 284-297
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Zebisch, M.; Schaefer, P.; Lauble, P.; Straeter, N.: New crystal forms of NTPDase1 from the bacterium Legionella pneumophila. , Acta Crystallographica Section F - Structural Biology and Crystallization Communications 69 (2013), p. 257-262
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Jakobi, Stephan: Nichtkompetitive Inhibition der tRNA-Guanin Transglycosylase durch Störung der essentiellen Protein-Protein-Interaktion. , Dissertation, Marburg, Philipps-Universität Marburg, 2013
Volkers, G.; Damas, J.M.; Palm, G.J.; Panjikar, S.; Soares, C.M.; Hinrichs, W.: Putative dioxygen-binding sites and recognition of tigecycline and minocycline in the tetracycline-degrading monooxygenase TetX. , Acta Crystallographica Section D - Biological Crystallography 69 (2013), p. 1758 - 1767
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Forst, A.H.; Karlberg, T.; Herzog, N.; Thorsell, A.-G.; Gross, A.; Feijs, K.L. H.; Verheugd, P.; Kursula, P.; Nijmeijer, B.; Kremmer, E.; Kleine, H.; Ladurner, A.G.; Schuler, H.; Luescher, B.: Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains. , Structure 21 (2013), p. 462-475
doi: 10.1016/j.str.2012.12.019
Schlechte, L.; Bon, V.; Grünker, R.; Klein, N.; Senkovska, I.; Kaskel, S.: Reprint of "Structural diversity of cobalt(II) coordination compounds involving bent imidazole ligand: A route from OD dimer to 3D coordination polymer". , Polyhedron 52 (2013), p. 1481-1488
doi: 10.1016/j.poly.2013.02.002
Nickerl, G.; Notzon, A.; Heitbaum, M.; Senkovska, I.; Glorius, F.; Kaskel, S.: Selective Adsorption Properties of Cationic Metal-Organic Frameworks Based on Imidazolic Linker. , Crystal Growth & Design 13 (2013), p. 198-203
doi: 10.1021/cg301347t
Wolters, S.; Neeb, M.; Berim, A.; Wischeler, J.S.; Petersen, M.; Heine, A.: Structural analysis of coniferyl alcohol 9-O-methyltransferase from Linum nodiflorum reveals a novel active-site environment. , Acta Crystallographica Section D - Biological Crystallography 69 (2013), p. 888-900
doi: 10.1107/S0907444913002874
Mayr, Florian: Structural and Functional Analysis of Lin28-Mediated Inhibition of let-7 miRNA Biogenesis. , Berlin, Freie Universität Berlin, Diss., 2013
Santos, Karine: Structural and functional studies of the spliceosomal RNP remodeling enzyme Brr2. , Uni Göttingen, 2013
Wandersleben, Traudy: Structural basis for dual regulation of spliceosomal helicase Brr2 by the Prp8 Jab1 domain and links to retinal disease. , Berlin, Freie Universität Berlin, Diss., 2013
Weber, G.; Cristao, V.F.; Santos, K.F.; Jovin, S.M.; Heroven, A.C.; Holton, N.; Luhrmann, R.; Beggs, J.D.; Wahl, M.C.: Structural basis for dual roles of Aar2p in U5 snRNP assembly. , Genes & Development 27 (2013), p. 525-540
doi: 10.1101/gad.213207.113
Schiefner, A.; Sinz, Q.; Neumaier, I.; Schwab, W.; Skerra, A.: Structural Basis for the Enzymatic Formation of the Key Strawberry Flavor Compound 4-Hydroxy-2,5-dimethyl-3(2H)-furanone. , Journal of Biological Chemistry 288 (2013), p. 16815-16826
doi: 10.1074/jbc.M113.453852
Zahn, M.; Berthold, N.; Kieslich, B.; Knappe, D.; Hoffmann, R.; Strater, N.: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. , Journal of Molecular Biology : jmb 425 (2013), p. 2463 - 2479
doi: 10.1016/j.jmb.2013.03.041
Malecki, P.H.; Raczynska, J.E.; Vorgias, C.E.; Rypniewski, W.: Structure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacterium. , Acta Crystallographica Section D - Biological Crystallography 69 (2013), p. 821-829
doi: 10.1107/S0907444913002011
Moser, J.; Lange, C.; Krausze, J.; Rebelein, J.; Schubert, W.-D.; Ribbe, M.W.; Heinz, D.W.; Jahn, D.: Structure of ADP-aluminium fluoride-stabilized protochlorophyllide oxidoreductase complex. , Proceedings of the National Academy of Sciences of the United States of America : PNAS 110 (2013), p. 2094-2098
doi: 10.1073/pnas.1218303110
Moser, J.; Lange, C.; Krausze, J.; Rebelein, J.; Schubert, W.-D.; Ribbe, M.W.; Heinz, D.W.; Jahn, D.: Structure of ADP-aluminium fluoride-stabilized protochlorophyllide oxidoreductase complex. , Proceedings of the National Academy of Sciences of the United States of America : PNAS 110 (2013), p. 2094-2098
doi: 10.1073/pnas.1218303110
Bauer, Johannes: Structure-Function Analyses of Two-Component Signaling in Arabidopsis Thaliana and Cellular Attachment Mechanisms of Adenovirus Type 37. , Tübingen, Eberhard Karls Universität, Diss., 2013
Welin, M.; Lehtio, L.; Johansson, A.; Flodin, S.; Nyman, T.; Tresaugues, L.; Hammarstrom, M.; Gräslund, S.; Nordlund, P.: Substrate Specificity and Oligomerization of Human GMP Synthetase. , Journal of Molecular Biology : jmb 425 (2013), p. 4323-4333
doi: 10.1016/j.jmb.2013.06.032
Angelucci, F.; Saccoccia, F.; Ardini, M.; Boumis, G.; Brunori, M.; Dileandro, L.; Ippoliti, R.; Miele, A.E.; Natoli, G.; Scotti, S.; Bellelli, A.: Switching between the Alternative Structures and Functions of a 2-Cys Peroxiredoxin, by Site-Directed Mutagenesis. , Journal of Molecular Biology : jmb 425 (2013), p. 4556-4568
doi: 10.1016/j.jmb.2013.09.002
Chang, K.; Fritz, M.A.; Tamm, N.B.; Goryunkov, A.A.; Sidorov, L.N.; Chen, C.; Yang, S.; Kemnitz, E.; Troyanov, S.I.: Synthesis, Structure, and Theoretical Study of Trifluoromethyl Derivatives of C84(22) Fullerene. , Chemistry - A European Journal 19 (2013), p. 577-586
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Bon, V.; Senkovska, I.; Weiss, M.S.; Kaskel, S.: Tailoring of network dimensionality and porosity adjustment in Zr- and Hf-based MOFs. , CrystEngComm 15 (2013), p. 9572-9577
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Kim, Yong Ju: The crystal structure of splice variant mutant of arrestin, p44 : the pre-active conformation of arrestin. , Diss., HU Berlin, 2013
Drozdzal, P.; Gilski, M.; Kierzek, R.; Lomozik, L.; Jaskolski, M.: Ultrahigh-resolution crystal structures of Z-DNA in complex with Mn2+ and Zn2+ ions. , Acta Crystallographica Section D - Biological Crystallography 69 (2013), p. 1180-1190
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Heiker, J.T.; Klöting, N.; Kovacs, P.; Kuettner, E.B.; Strüter, N.; Schultz, S.; Kern, M.; Stumvoll, M.; Blüher, M.; Beck-Sickinger, A.G.: Vaspin inhibits kallikrein 7 by serpin mechanism. , Cellular and Molecular Lilfe Sciences 70 (2013), p. 2569-2583
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Jeoung, J.-H.; Bommer, M.; Lin, T.-Y.; Dobbek, H.: Visualizing the substrate-, superoxo-, alkylperoxo-, and product-bound states at the nonheme Fe(II) site of homogentisate dioxygenase. , Proceedings of the National Academy of Sciences of the United States of America : PNAS 110 (2013), p. 12625-12630
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Biela, A.; Nasief, N.; Betz, M.; Heine, A.; Hangauer, D.; Klebe, G.: Zerlegung des hydrophoben Effekts auf molekularer Ebene: Die Rolle von Wasser, Enthalpie und Entropie bei der Ligandenbindung an Thermolysin. , Angewandte Chemie 125 (2013), p. 1868-1876
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Bon, V.; Senkovska, I.; Baburin, I.A.; Kaskel, S.: Zr- and Hf-Based Metal-Organic Frameworks: Tracking Down the Polymorphism. , Crystal Growth & Design 13 (2013), p. 1231-1237
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Kishko, I.; Carey, J.; Reha, D.; Brynda, J.; Winkler, R.; Harish, B.; Guerra, R.; Ettrichova, O.; Kukacka, Z.; Sheryemyetyeva, O.; Novak, P.; Kuty, M.; Smatanova, I.K.; Ettrich, R.; Lapkouski, M.: 1.2 angstrom resolution crystal structure of Escherichia coli WrbA holoprotein. , Acta Crystallographica Section D - Biological Crystallography 69 (2013), p. 1748-1757
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2012
Hauptvogel, I.M.; Bon, V.; Grünker, R.; Baburin, I.A.; Senkovska, I.; Mueller, U.; Kaskel, S.: A family of 2D and 3D coordination polymers involving a trigonal tritopic linker. , Dalton Transactions 41 (2012), p. 4172-4179
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Strianese, M.; Palm, G.J.; Milione, S.; Kühl, O.; Hinrichs, W.; Pellecchia, C.: A FRET Enzyme-Based Probe for Monitoring Hydrogen Sulfide. , Inorganic Chemistry 51 (2012), p. 11220-11222
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Stoeck, U.; Krause, S.; Bon, V.; Senkovska, I.; Kaskel, S.: A highly porous metal-organic framework, constructed from a cuboctahedral super-molecular building block, with exceptionally high methane uptake. , Chemical Communications 48 (2012), p. 10841-10843
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Lincke, J.; Lässig, D.; Kobalz, M.; Bergmann, J.; Handke, M.; Möllmer, J.; Lange, M.; Roth, C.; Möller, A.; Staudt, R.; Krautscheid, H.: An Isomorphous Series of Cubic, Copper-Based Triazolyl Isophthalate MOFs: Linker Substitution and Adsorption Properties. , Inorganic Chemistry 51 (2012), p. 7579-7586
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Hilberg, Markus: Anaerober Toluol-Stoffwechsel in Thauera aromatica: Biochemische und spektroskopische Untersuchungen zur Reaktion der (R)-Benzylsuccinat Synthase. , Uni Marburg, 2012
Steinmetzer, T.; Baum, B.; Biela, A.; Klebe, G.; Nowak, G.; Bucha, E.: Beyond heparinization: design of highly potent thrombin inhibitors suitable for surface coupling. , ChemMedChem 7 (2012), p. 1965-1973
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Hee, C.S.; Fabian, H.; Uchanska-Ziegler, B.; Ziegler, A.; Loll, B.: Comparative biophysical characterization of chicken β2-microglobulin. , Biophysical Chemistry 167 (2012), p. 26-35
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El Malah, T.; Ciesielski, A.; Piot, L.; Troyanov, S.I.; Müller, U.; Weidner, S.; Samori, P.; Hecht, S.: Conformationally pre-organized and pH-responsive flat dendrons: synthesis and self-assembly at the liquid-solid interface. , Nanoscale 4 (2012), p. 467-472
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Sun, L.; Chen, Y.; Rajendran, C.; Mueller, U.; Panjikar, S.; Wang, M.; Mindnich, R.; Rosenthal, C.; Penning, T.M.; Stoeckigt, J.: Crystal Structure of Perakine Reductase, Founding Member of a Novel Aldo-Keto Reductase (AKR) Subfamily That Undergoes Unique Conformational Changes during NADPH Binding. , Journal of Biological Chemistry 287 (2012), p. 11213-11221
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Chauviac, F.-X.; Bommer, M.; Yan, J.; Parkin, G.; Daviter, T.; Lowden, P.; Raven, E.L.; Thalassinos, K.; Keep, N.H.: Crystal Structure of Reduced Msacg, a Putative Nitroreductase from Mycobacterium Smegmatis and a Close Homologue of Mycobacterium Tuberculosis Acg. , Journal of Biological Chemistry 287 (2012), p. 44372-44383
doi: 10.1074/jbc.M112.406264
Knapp, K.; Zebisch, M.; Pippel, J.; El-Tayeb, A.; Mueller, C.E.; Sträter, N.: Crystal Structure of the Human Ecto-5'-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling. , Structure 20 (2012), p. 2161-2173
doi: 10.1016/j.str.2012.10.001
Schreiner, M.; Niemann, H.H.: Crystal structure of the Yersinia enterocolitica type III secretion chaperone SycD in complex with a peptide of the minor translocator YopD. , BMC Structural Biology 12 (2012), p. 13/1-9
doi: 10.1186/1472-6807-12-13
Martinez, J.; Nguyen, L. D.; Hinderlich, S.; Zimmer, R.; Tauberger, E.; Reutter, W.; Saenger, W.; Fan, H.; Moniot, S.: Crystal Structures of N-Acetylmannosamine Kinase Provide Insights into Enzyme Activity and Inhibition. , Journal of Biological Chemistry 287 (2012), p. 13656-13665
doi: 10.1074/jbc.M111.318170
Bulut, H.; Moniot, S.; Licht, A.; Scheffel, F.; Gathmann, S.; Saenger, W.; Schneider, E.: Crystal Structures of Two Solute Receptors for L-Cystine and L-Cysteine, Respectively, of the Human Pathogen Neisseria gonorrhoeae. , Journal of Molecular Biology : jmb 415 (2012), p. 560
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Roth, C.; Kaschabek, S.R.; Gröning, J.A.D.; Handrek, T.; Schlömann, M.; Straeter, N.: Crystallization and preliminary characterization of chloromuconolactone dehalogenase from Rhodococcus opacus 1CP. , Acta Crystallographica Section F - Structural Biology and Crystallization Communications 68 (2012), p. 591-595
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2006
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2005
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2004
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Layer, G.; Moser, J.; Heinz, D.W.; Jahn, D.; Schubert, W.-D.: Crystal Structure of Coproporphyrinogen III Oxidase Reveals Cofactor Geometry of Radical Sam Enzymes. , The EMBO Journal 22 (2003), p. 6214-6224
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MX 14.2