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Joint Research Group Macromolecular Crystallography

Our MX team is located at  the Wilhelm-Conrad-Röntgen Campus of the HZB in Berlin-Adlershof. We are responsible for the operation, maintenance and development of three synchrotron beamlines for macromolecular crystallography at the BESSY-II electron storage ring.

Beamlines 14.1 and 14.2 are dedicated to multi-wavelength-anomalous dispersion (MAD) phasing methods operating between 5.5-15.5 keV (2.25 to 0.75 Å), which cover the absorption edges of most commonly used heavy atom derivatives. State-of-the-art detector technologies, including the PILATUS 6M (BL14.1) and PILATUS3S 2M (BL14.2) detectors (Dectris, Switzerland), enable high quality and rapid data collection. Fast and reliable sample changing is realized by automated samples changing robots CATS and G-ROB employed on both beamlines 14.1 and 14.2, respectively. Beamline 14.3 is a fixed energy station operating at 13.87 keV (0.89 Å).

The infrastructure adjacent to the experimental end stations offers excellent facilities for users of the beamlines and includes office space, a sample preparation lab, a biology lab (safety level 1), and computing resources. And of course, the competent HZB MX-team will assist you before and during your beamtime. The success of the HZB MX-beamlines is documented by more than 3000 PDB entries from experimental beamtime of more than hundred international user groups from academia and pharmaceutical research companies.