HZB and Freie Universität Berlin establish the joint research group “X-Ray Microscopy” for studying complex cellular processes
In May this year, the joint research group “X-Ray Microscopy” was launched, combining the expertise of teams led by Prof. Dr. Gerd Schneider (Helmholtz-Zentrum Berlin) and Prof. Dr. Helge Ewers (Freie Universität Berlin). While Ewers’ group contributes its experience in the field of optical microscopy and biological research, the HZB workgroup is responsible for X-ray microscopy at the synchrotron source BESSY II. The two methods help researchers to gain a detailed insight into the processes taking place inside cells.
We are very pleased about the new cooperation with Prof. Ewers’ workgroup. It gives our own activities in this field a much stronger connection to the biological research being done at the university,” says Prof. Dr. Gerd Schneider. The core duties of his department at HZB include making advancements to the x-ray microscopes and lenses at the synchrotron source BESSY II. The active exchange between the new cooperation partners will give a new boost to method development, says Schneider. Prof. Dr. Helge Ewers is also excited about the future-oriented cooperation: “X-ray microscopy opens up entirely new possibilities for us in the research of intracellular processes.”
The joint research group is all about the complementary use of optical and X-ray microscopy. Optical microscopy and super-resolution methods are excellent for locating proteins marked with dye molecules in tissue samples. X-ray microscopy, in turn, allows correlative imaging of the distribution of proteins, viruses or nanoparticles over a relatively large section in high-resolution and three-dimensions. The two microscopy methods thus deliver a comprehensive picture of the intracellular structures and processes.
After a successful upgrade, the X-ray microscope TXM at the synchrotron source BESSY II is now available again to users. Aside from biological studies, which can now be conducted with the combined expertise in the joint research group, the X-ray microscope is used above all for exploring various questions of materials and energy research.
- Energy of charge carrier pairs in cuprate compoundsHigh-temperature superconductivity is still not fully understood. Now, an international research team at BESSY II has measured the energy of charge carrier pairs in undoped La₂CuO₄. Their findings revealed that the interaction energies within the potentially superconducting copper oxide layers are significantly lower than those in the insulating lanthanum oxide layers. These results contribute to a better understanding of high-temperature superconductivity and could also be relevant for research into other functional materials.
- Electrocatalysis with dual functionality – an overviewHybrid electrocatalysts can produce green hydrogen, for example, and valuable organic compounds simultaneously. This promises economically viable applications. However, the complex catalytic reactions involved in producing organic compounds are not yet fully understood. Modern X-ray methods at synchrotron sources such as BESSY II, enable catalyst materials and the reactions occurring on their surfaces to be analysed in real time, in situ and under real operating conditions. This provides insights that can be used for targeted optimisation. A team has now published an overview of the current state of knowledge in Nature Reviews Chemistry.
- BESSY II: Phosphorus chains – a 1D material with 1D electronic propertiesFor the first time, a team at BESSY II has succeeded in demonstrating the one-dimensional electronic properties in phosphorus. The samples consisted of short chains of phosphorus atoms that self-organise at specific angles on a silver substrate. Through sophisticated analysis, the team was able to disentangle the contributions of these differently aligned chains. This revealed that the electronic properties of each chain are indeed one-dimensional. Calculations predict an exciting phase transition to be expected as soon as these chains are more closely packed. While material consisting of individual chains with longer distances is semiconducting, a very dense chain structure would be metallic.