HZB and Freie Universität Berlin establish the joint research group “X-Ray Microscopy” for studying complex cellular processes
In May this year, the joint research group “X-Ray Microscopy” was launched, combining the expertise of teams led by Prof. Dr. Gerd Schneider (Helmholtz-Zentrum Berlin) and Prof. Dr. Helge Ewers (Freie Universität Berlin). While Ewers’ group contributes its experience in the field of optical microscopy and biological research, the HZB workgroup is responsible for X-ray microscopy at the synchrotron source BESSY II. The two methods help researchers to gain a detailed insight into the processes taking place inside cells.
We are very pleased about the new cooperation with Prof. Ewers’ workgroup. It gives our own activities in this field a much stronger connection to the biological research being done at the university,” says Prof. Dr. Gerd Schneider. The core duties of his department at HZB include making advancements to the x-ray microscopes and lenses at the synchrotron source BESSY II. The active exchange between the new cooperation partners will give a new boost to method development, says Schneider. Prof. Dr. Helge Ewers is also excited about the future-oriented cooperation: “X-ray microscopy opens up entirely new possibilities for us in the research of intracellular processes.”
The joint research group is all about the complementary use of optical and X-ray microscopy. Optical microscopy and super-resolution methods are excellent for locating proteins marked with dye molecules in tissue samples. X-ray microscopy, in turn, allows correlative imaging of the distribution of proteins, viruses or nanoparticles over a relatively large section in high-resolution and three-dimensions. The two microscopy methods thus deliver a comprehensive picture of the intracellular structures and processes.
After a successful upgrade, the X-ray microscope TXM at the synchrotron source BESSY II is now available again to users. Aside from biological studies, which can now be conducted with the combined expertise in the joint research group, the X-ray microscope is used above all for exploring various questions of materials and energy research.
- BESSY II: How intrinsic oxygen shortens the lifespan of solid-state batteriesAlthough solid-state batteries (SSBs) demonstrate high performance and are intrinsically safe, their capacity currently declines rapidly. A team from the TU Wien, Humboldt-University Berlin and HZB has now analysed a TiS₂|Li₃YCl₆ solid-state half-cell in operando at BESSY II using a special sample environment that allows for non-destructive investigation under real operating conditions. Data obtained by combination of soft and hard X-ray photoelectron spectroscopy (XPS and HAXPES) revealed a new degradation mechanism that had not previously been identified in solid-state batteries. They have gained some surprising insights, particularly regarding the harmful role played by intrinsic oxygen. This study provides valuable information for improving design and handling of such batteries.
- Spintronics at BESSY II: Real-time analysis of magnetic bilayer systemsSpintronic devices enable data processing with significantly lower energy consumption. They are based on the interaction between ferromagnetic and antiferromagnetic layers. Now, a team from Freie Universität Berlin, HZB and Uppsala University has succeeded in tracking, for each layer separately, how the magnetic order changes after a short laser pulse has excited the system. They were also able to identify the main cause of the loss of antiferromagnetic order in the oxide layer: the excitation is transported from the hot electrons in the ferromagnetic metal to the spins in the antiferromagnet.
- Environmental Chemistry at BESSY II: Radicals in waterwaysHow do radicals form in aqueous solutions when exposed to UV light? This question is important for health research and environmental protection, for example with regard to the overfertilisation of water bodies by intensive agriculture. A team at BESSY II has now developed a new method of investigating hydroxyl radicals in solution. By using a clever trick, the scientists gained surprising insights into the reaction pathway.