Artificial evolution for medical application

Prof. Dr. Andreas Marx is this year’s recipient of the Karl Heinz Beckurts Award.

Prof. Dr. Andreas Marx is this year’s recipient of the Karl Heinz Beckurts Award.

2014 Karl Heinz Beckurts Award goes to Prof. Dr. Andreas Marx

Prof. Dr. Andreas Marx of the University of Konstanz is this year’s recipient of the Karl Heinz Beckurts Award. The 30,000 Euro award will be presented to Marx on Monday, December 1, 2014, at 5:30 pm in Max-Joseph-Saal at the Munich Residenz. With its nomination, the Beckurt Foundation is recognizing a scientist whose truly interdisciplinary way of thinking has inspired him to join together the scientific disciplines of chemistry, biology, and biotechnology. Marx’ approach has already resulted in important applications that have since found their way into medical diagnostics and cancer therapy, among others.

The focus of Andreas Marx’ research is on the biochemistry of DNA polymerases, the group of enzymes that is in charge of making sure the genetic material is replicated properly during cell division: The job of the polymerases is to create copies of the original DNA, which are ultimately distributed among the daughter cells. With his research, Andreas Marx has laid the foundation for science’s ability to modify DNA polymerases. Simulating evolution in his lab, Marx and his team have developed protocols for high-throughput screening of polymerases for any modification that makes them particularly well-suited for certain applications – like, for instance, early diagnosis of cancer.

“Especially set against the background of an aging society, Andreas Marx’ research has several important implications,“ stresses Prof. Dr. Anke Kaysser-Pyzalla, chairwoman of the Karl Heinz Beckurts Foundation and the Helmholtz Center Berlin’s scientific director. “It’s helped give physicians a greater sense of security with respect to diagnosis, treatment, and prognosis of disease. Thanks to Marx’ work, therapies have become more targeted, have produced increases in patients’ quality of life, and have helped offset the high costs associated with imprecise diagnoses.“ 

The Karl Heinz Beckurts Foundation was founded by the Helmholtz Association in 1987 in memory of researcher and manager Prof. Dr. Karl Heinz Beckurts. From 1973 to 1976, Beckurts was head of the large-scale equipment work group (GF, the organization that would years later become the Helmholtz Association). In 1976, Beckurts became chairman of what was then the Jülich Nuclear Research Facility and, in 1980, became a member of the board of the Siemens AG. In 1986, Beckurts became the tragic victim of a terrorist attack. The Foundation’s annual award is given in recognition of exceptional scientific and technological achievements that are relevant to industry.


You might also be interested in

  • Professorship at the University of Augsburg for Felix Büttner
    Professorship at the University of Augsburg for Felix Büttner
    Felix Büttner has led a junior research group at HZB. Now he has accepted a call to the University of Augsburg. As head of a joint research group, he will continue his studies of magnetic skyrmions at BESSY II.
  • Humboldt Fellow Alexander Gray comes to HZB
    Humboldt Fellow Alexander Gray comes to HZB
    Alexander Gray from Temple University in Philadelphia, USA, is working with HZB physicist Florian Kronast to investigate novel 2D quantum materials at BESSY II. With the fellowship from the Alexander von Humboldt Foundation, he can now deepen this cooperation. At BESSY II, he wants to further develop depth-resolved X-ray microscopic and spectroscopic methods in order to investigate 2D quantum materials and devices for new information technologies even more thoroughly.
  • Young investigator research group on electrocatalysis at HZB
    Young investigator research group on electrocatalysis at HZB
    Dr. Michelle Browne establishes her own young investigator group at the HZB . Starting in August, the group is co-funded by the Helmholtz Association for the next five years. The electrochemist from Ireland concentrates on electrolytically active novel material systems and wants to develop next-generation electrocatalysts, for example hydrogen production. At HZB she will find the perfect environment to conduct her research.