Joint Research Group Macromolecular Crystallography
12. Joint Berlin MX-day
Charité CrossOver building
Charité – Universitätsmedizin Berlin
Charitéplatz 1
9. July 2025
12. Joint MX-Day participants at July 9th 2025
Meeting Agenda
| 09:30 - 10:00 | Coffee |
| 10:00 - 10:10 | Patrick Scheerer & Manfred Weiss Greetings |
| Session I – Structural Biology Core Facilities Berlin (Patrick Scheerer, Charitè) | |
| 10:10 ‐ 10:22 | Uwe Mueller (HZB) Facilities for Macromolecular Crystallography at the HZB |
| 10:22 ‐ 10:34 |
Peter Schmieder (NMR Facility Berlin – FMP) The NMR-Facility of the FMP: Investigation of Proteins and small molecules |
| 10:34 ‐ 11:46 |
Tarek Hilal (Core Facility BioSupraMol – FUB) CryoEM at the Interface: Visualizing Molecules and Materials Across Disciplines |
| 11:46 ‐ 11:00 |
Thiemo Sprink (Core Facility for cryo Electron Microscopy (CFcryoEM) – Charité/ MDC) Structural Journeys from Biochemical Purity to Cellular Reality: Advancing Structural Biology in vitro and in situ with Cryo-EM/ET |
| Session II
Protein Mechanisms and Molecular Function (Chair: (Holger Dobbek, HU-Berlin) |
|
| 11:00 - 11:15 |
Yudhajeet Basak (Group Dobbek – HUB) Deciphering CO2 Reduction in Ni,Fe-CODHs: A Combinatorial Approach |
| 11:15 - 11:30 |
Karoline-Luisa Lê Công (Group Heberle – FUB & Group Scheerer – Charité) How backbone motions modulate the photocycle of a microbial chloride pump
|
| 11:30 - 11:45 |
Malkeet Singh (Group Roth – FUB)
Structural and functional insight into the nucleotide specificity of glycocin glycosyltransferases |
| 11:45 - 12:00 |
Jana Sticht (Group Freund – FU) Actin polymerization and bundling by an intrinsically disordered protein region
|
| 12:00 - 13:30 | Group Foto & Lunch |
| Session III –
Membrane Proteins with cryo-EM/ET (Chair: Oliver Daumke MDC) |
|
| 13:30 ‐ 13:45 |
Monique Gallandi (Group Scheerer – Charité) Structure-based development of new drugs for the appetite-regulating MC4 Receptor |
| 13:45 ‐ 14:00 |
Daniel Roderer (Group Roderer – FMP) Structural basis of immune cell deactivation by fusobacterial adhesins |
| 14:15 - 15:00 |
SESSION IV: Gene Regulation and Translation (Chair: Petra Wendler UP) |
| 14:15 ‐ 14:30 |
Muriel Hartsch (Group Milles – FMP) Structural dynamics and long-range interactions controlling timing of the Neurospora circadian |
| 14:30 - 14:45 |
Zhennan Tian (Group Wahl – FUB) Structural basis for the autogenous control of the rpsJ operon |
| 14:45 - 15:00 |
Yollete Guillén-Schlippe (Group Spahn – Charité) Comprehensive visualization of actively translating polysomes by cryo-EM
|
| 15:00 ‐ 15:45 | Coffee Break |
|
15;45 - 17:00 |
Session V –
Emerging Methods in Structural Biology (Chair: Sutapa Chakrabarti, FUB) |
| 15:45 ‐ 16:00 |
Tatjana Barthel (Group Weiss – HZB) News from the F2X facility – fragment-screening by crystallography |
| 16:00 ‐ 16:15 |
Ashwin Karthick Natarajan (Group Daumke – MDC) From DNA Donuts to Pointers: Engineering DNA-based scaffolds for Protein Structure Analysis |
| 16:15 ‐ 16:30 |
Taoran Xiao & Denis Qoraj (Group Lange – FMP) Integrated cryo-EM and solid-state NMR investigation of membrane- embedded channels |
| 16:30 ‐ 16:45 |
Jakob Ruickoldt (Group Wendler – UP) CryoPike- using AI to optimise Cryo EM data aquisition |
| 16:45 - 17:00 |
Guillermo Pérez-Hernández (Group Scheerer – Charité) GPCR – protein Complexes in Motion: Cryo-EM and Molecular Dynamics at the interface of the β2AR-GsGDP/GTP system |
| 17:00 - 17:15 |
inal Remarks by Patrick Scheerer (Charité) & Manfred Weiss (HZB) |
| 17:15 - | BBQ - Dinner Get Together |
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| 18:00 ‐ end | BBQ |
Joint Berlin MX Laboratory Partners
